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Clinical Trial Summary

The purpose of this double-blind study is to determine the effect of reducing oxalates in the diet of healthy volunteers by using Nephure, an oxalate-reducing enzyme, as compared to placebo.


Clinical Trial Description

This study aims at evaluating the effect from Nephure in reducing dietary oxalate in healthy volunteers on a controlled diet as compared to placebo. Subjects are on a normal diet with controlled oxalate (750mg/day) and calcium (550mg/day) levels for 8 consecutive days. The study is a cross-over design with two four-day treatment periods. The study intends to determine level of reduction in urinary oxalate output as a measure of the effect of Nephure on dietary oxalate when ingested with a meal. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03661216
Study type Interventional
Source Captozyme, Inc.
Contact
Status Completed
Phase N/A
Start date July 11, 2018
Completion date August 5, 2018

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