Healthy Clinical Trial
Official title:
Investigation of the Relationship Between Taste Perception and Caries Activity in School Children
Four basic taste perceptions and relationship with caries are poorly investigated in children
as compared to adults.
The aim of this study was to evaluate salty, sweet, bitter and sour taste perceptions of
school children and compare them with demographic, clinical, microbiologic and biochemical
caries-risk factors.
Study design
1. Caries risk assessment The investigators developed a questionnaire to understand the
patient's overall health status, to collect demographic and socio-economic information,
to assess their oral health habits. The questionnaire consists of 3 parts; first part
includes questions about general health such as chronic diseases, drugs and allergies,
second part includes questions about income and education level of parents, and last
part includes questions about oral health knowledge, habits, diet contents and
frequency, fluoride exposure. the investigators allowed the parents to fill the
questionnaire.
After the questionnaire was filled, the investigators performed the oral examination
using DMFT, DMFS, dft and dfs indices according to WHO. Then, the investigators
determined the oral hygiene status with Sillness&Löe Index (Silness ve Loe, 1964). the
investigators estimated paraffin-stimulated salivary flow rate, buffer capacity, mutans
streptococci and lactobacilli counts using CRT chairside kits (Ivoclar Vivadent, Schaan,
Liechtenstein).
In addition to initial questionnaire and oral examination, the investigators asked the
patients to record their nutritional takings of 2 weekdays and 1 weekend day. the
investigators estimated the caries risk profiles of all children using the Cariogram
which is a computer-based program. Cariogram identifies three risk groups low, medium
and high caries risk according the scores.
2. Taste evaluation the investigators prepared aqueous basic taste solutions of sucrose
(Merck, Germany, purity >99.5%), sodium chloride (Sigma-Aldrich, USA, purity >99%),
caffeine (Merck, Germany, purity >99.5%), citric acid monohydrate (Sigma-Aldrich, USA,
purity >99%), at two levels (1.0 ISO, 2.0 ISO) (ISO 3972:1991, 8586-1:1993) (Table 1).
the investigators formulated all the solutions by using spring water in the same day of
measurement at room temperature (25 ± 2°C). Each solution was coded randomly.
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