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Network-Level Effects of Nitrous Oxide in the Human Brain

Healthy Clinical Trial

Official title:
Network-Level Effects of Nitrous Oxide in the Human Brain

Clinical Trial Summary

The purpose of this study is to understand how a commonly used drug, nitrous oxide, acts on the brain to reduce pain. Nitrous oxide is commonly used in anesthesiology but there is limited knowledge on how this drug affects functional networks in the brain.

Clinical Trial Description

The objective of this study is to identify the network transformations that account for the analgesic effects of nitrous oxide. Our hypothesis is that analgesic doses of nitrous oxide increase network efficiency and disrupt normal pain processingOur approach is to administer subanesthetic nitrous oxide during the acquisition of fMRI (functional magnetic resonance imaging) and EEG (electroencephalogram). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03435055
Study type Interventional
Source University of Michigan
Contact
Status Completed
Phase Phase 4
Start date July 21, 2017
Completion date October 11, 2019
View Details
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