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Gut Microbial Metabolism of Polyphenols and Cardiovascular Health (StratiPol) (Stratification Study) — StratiPol  

Healthy Clinical Trial

Official title:
Gut Microbial Metabolism of Polyphenols and Cardiovascular Health

Clinical Trial Summary

There is increasing interest in the effects of various food derived polyphenols on cardiovascular health. Several studies have demonstrated improvements in vascular function after intake of polyphenol rich foods. The objective of this study is to investigate the association between polyphenol microbiota metabolism and cardiovascular health. The participants (n=250) with age range between 20 to 70 years old health overweight men and women. The participants will consume a polyphenol rich breakfast for three days (consisting on milled flaxseed, raspberry powder and soy milk). The participants will provide the investigators with urine and blood samples for polyphenol analysis. Cardiovascular measurements such as PWV, AIx, Blood Pressure and FMD will be performed at baseline and after 72h.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03573414
Study type Interventional
Source King's College London
Contact Julia Casani-Cubel, MBBS
Phone +44 (0) 20 7848 4162
Email julia.casani@kcl.ac.uk
Status Recruiting
Phase N/A
Start date July 2, 2018
Completion date September 2022
View Details
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