NG101m Adjuvant Therapy in Glioblastoma Patients

Status Not yet recruiting

Clinical Trial Summary

The purpose of this clinical trial is to evaluate the addition of NG101m adjuvant therapy to standard of care treatment of glioblastoma multiforme. All subjects will receive NG101m capsules along with the standard treatment of temozolomide and radiation.

Clinical Trial Description

Glioblastoma multiforme (GBM) is the most lethal form of malignant brain cancer, with about 12,000 new cases diagnosed each in the the United States. The current standard treatment consists of maximal, safe resection, followed by radiation therapy of 60 Gray (Gy) with concomitant oral temozolomide (TMZ) for 6 weeks, then continue with six cycles of high-dose temozolomide. The median survival rate for newly diagnosed GBM patients is 14.6 months with a 2-year overall survival (OS) rate of 27.2%. This clinical trial evaluates the 2-year OS of oral NG101m as an adjuvant therapy to chemoradiotherapy in newly diagnosed GBM subjects. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04373785
Study type	Interventional
Source	NeuGATE Theranostics
Contact	Thien Tran, PharmD
Phone	713-534-1300
Email	TTran@NeuGATE.org
Status	Not yet recruiting
Phase	Phase 1/Phase 2
Start date	January 1, 2024
Completion date	December 31, 2027

View Details

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