PRF for Accelerating Palatal Healing

Status Completed

Clinical Trial Summary

Backgroung: Various agents are used to reduce post-operative complications associated with palatal donor site surgery for free gingival graft (FGG) harvesting. This study was conducted to evaluate the effects of platelet-rich fibrin (PRF) on palatal wound healing.

Clinical Trial Description

125 patients with isolated recessions were treated. The connective tissue graft was obtained by the de-epithelialization of a free gingival graft in both groups. Three different hemostatic treatments were randomized; PRF with cyanoacrilate adhesive (PRF group, n:42), cyanoacrilate adhesive alone (BC group, n:42) and sterile wet gauze compression (WG group, n:41). Immediate and delayed bleeding, pain, epithelialization, feeding habits and sensation scores were recorded for different time points. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

Gingival Recession

Clinical Trial Details

NCT number	NCT02712242
Study type	Interventional
Source	Cukurova University
Contact
Status	Completed
Phase	N/A
Start date	November 2013
Completion date	September 2015

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04462237` - Recombinant Human Platelet-derived Growth Factor in Combination With Collagen Matrix	N/A
Enrolling by invitation	`NCT05591326` - The Effect of Using Injectable Platelet-rich Fibrin on Root Surface Closure in Patients With Gingival Recession.	N/A
Completed	`NCT06118177` - Ultrasonographic Assessment of Palatal Wound Healing
Not yet recruiting	`NCT06044727` - MINST Versus Conventional Subgingival Instrumentation In RT1 Gingival Recession	N/A
Not yet recruiting	`NCT06044870` - Clinical Evaluation of the Modified Laterally Stretched Technique (RT2) Gingival Recession vs Tunneling With CT Grafting	Phase 2
Recruiting	`NCT02995070` - Low Intensity Laser Therapy in Connective Tissue Graft for Root Coverage in Smokers	N/A
Completed	`NCT03204565` - Effectiveness of Adjunctive Hyaluronic Acid Application in Coronally Advanced Flap in Single Gingival Recession Sites	N/A
Completed	`NCT01440426` - Connective Tissue Graft Versus Mucograft Collagen Matrix for Coverage of Multiple Gingival Recession Defects	Phase 4
Completed	`NCT02129504` - Two Techniques for Root Coverage With a Xenogeneic Collagen Matrix	N/A
Completed	`NCT01547962` - A Pilot Clinical Trial of Gintuit (TM)in Establishing a Functional Zone of Attached Gingiva	N/A
Completed	`NCT04043039` - Platelet Rich Fibrin in the Treatment of Full Thickness Palatal Wounds	N/A
Recruiting	`NCT04920136` - Gain of Keratinized Mucosa Around Teeth and Dental Implants Using a Combination of Strip Gingival Graft and Acellular Dermal Matrix	N/A
Active, not recruiting	`NCT03570333` - Progenitor Potential of Mesenchymal Stem Cells in Palatal Tissue Harvested From Molar and Premolar Sites	N/A
Recruiting	`NCT05045586` - MCAT With HA and sCTG Compared With sCTG Alone for Treatment of Multiple Gingival Recession: Clinical Trial	N/A
Active, not recruiting	`NCT05101642` - Guided Creeping Technique (GCT) in Treating Gingival Recession	N/A
Completed	`NCT04813302` - Influence of Anatomical Factors Upon Root Coverage	N/A
Recruiting	`NCT06006780` - Porcine Acellular Dermal Matrix for the Treatment of Localized Gingival Recessions A Multicenter Randomized Clinical Trial.	N/A
Enrolling by invitation	`NCT06330662` - Effectiveness of Hyaluronic Acid on Multiple Adjacent Gingival Recessions Using a Coronally Advanced Flap	N/A
Not yet recruiting	`NCT05472233` - Effect of Suturing Protocols on Coronally Advanced Flap for Root Coverage Outcomes	N/A
Recruiting	`NCT05563428` - Free Gingival Graft Versus Connective Tissue Graft	N/A