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Clinical Trial Summary

To establish to what degree individuals can increase esophageal high pressure zone (HPZ) after instruction in deep breathing as evidenced by concurrent manometric pressure readings.


Clinical Trial Description

Pressure in the lower esophagus has been negatively associated with reflux symptoms: the lower the pressure, the more reflux symptoms. This pressure can be augmented with deep abdominal breathing. This can be detected during esophageal manometry, when a pressure catheter is placed into the esophagus. Manometry is routinely done for swallowing disorders.

This study will take place just after a routine manometry test, when the subject still has the catheter in place. All that is required for the research portion is to observe manometry readings while they breathe, then when they deep breath, then breathe after they have been cued or coached to deep abdominal breathing. This is done in sequence to establish how quickly this pressure can be improved.

This coached breathing is then prescribed as a routine exercise and long term follow up performed via phone to see how their reflux symptoms have responded. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03495219
Study type Observational
Source Mayo Clinic
Contact Christopher J Yelvington, DPT
Phone 8502064596
Email yelvington.c@mayo.edu
Status Not yet recruiting
Phase
Start date May 1, 2018
Completion date July 30, 2018

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