Frailty Clinical Trial
Official title:
FOCUS- Frailty Management Optimization Through EIP AHA Commitments and Utilization of Stakeholders Input (WP7-WMU)
This intervention study is a part of the FOCUS (Frailty Management Optimization Through EIP
AHA Commitments and Utilization of Stakeholders Input) project which purpose is to critically
reduce the burden of frailty in Europe by assisting those partners within the European
Innovation Partnership for Active Healthy Ageing (EIPAHA) with commitments focusing on early
diagnosis/ screening and/or management of frailty to achieve scalability.
FOCUS aims to critically reduce the burden of frailty in Europe by developing methodologies
and tools to assist entities focusing on early diagnosis, screening and management of frailty
to achieve scalability. Frailty is a common clinical syndrome in older adults that brings an
increased risk for poor health outcomes including falls, incident disability, hospitalization
and mortality.
The FOCUS Consortium brings together a multidisciplinary team of specialists from 10
organizations in 6 countries - Italy, Poland, Portugal, Spain, Netherlands, United Kingdom -
that will work on developing, piloting and disseminating methodologies and tools to assist
entities focusing on early diagnosis, screening and management of frailty to achieve
scalability.
Wroclaw Medical University actively participates in all projects for the advances in science,
entrepreneurship, technological innovation, both with public authorities, local governments,
and enterprises. In FOCUS project, WMU is responsible for Evaluation of the project and
collaborates with the others partners in Coordination of the project, Dissemination of the
project, Synthesis of learning and realities of practice, Analysis and guidelines
development, Creation of Network and Platform for knowledge exchange, Test of guidelines in a
set of commitments (Work Package 7 - WP7).
The outcomes of this proposal will offer significant potential improvements for innovative,
coordinated and comprehensive community based prevention with regard to the optimisation of
functional capacity tools to address pre-frailty, and for improving the management of
frailty.
The registered study has its own protocol developed by Wroclaw Medical University research
team and will be implemented within WP7 of the FOCUS project.
This is a prospective intervention study. The study is expected screening about 320
participants - persons aged more than 60 years old recruited from Universities of the Third
Age, day care centers, primary care centers, geriatrics out-patient clinics and from nursing
homes. We are expected to enroll 270 potential participants (at least 135 participants) to 5
groups: 4 intervention groups and 1 control group without any intervention.
Patient qualification is based on criteria developed by Fried et al 2001.
Dimensions:
Weight loss Exhaustion Physical Activity Walk Time Grip Strength
INTERPRETATION:
Robust: 0 points Pre-frail: 1-2 points Frail: 3 or more points
Method: diagnostic survey Technique: the 'surveys combined with direct measurements of
patients investigated within 0, after 3 and 6 months
Tools:
Study questionnaires:
• Standardized questionnaires: Center for Epidemiologic Studies Depression Scale Minnesota
Leisure Time Physical Activity Questionnaire Vulnerable Elders — 13 Survey Mini Nutritional
Assessment Health Behaviour Inventory Montreal Cognitive Assessment Geriatric Depression
Scale World Health Organization Quality of Life (short version) questionnaire Camberwell
Assessment of Need Short Appraisal Schedule Barthel Scale Activities of Daily Living
Instrumental Activities of Daily Living Camberwell Assessment of Need Short Appraisal
Schedule Timed up and go test Beck Depression Inventory
- The questionnaire on: socio-demographic data - age, gender, marital status, living in
relationship/ without relationship, level of education, place of residence, economic
status; the number of hospitalizations in the last 3 years (including kind of ward); the
number and kind of chronic diseases (ICD-10); the number of permanent medications;
employment situation; number of traveling in the last year; having pets; number of
languages the participants can speak; number of falls
- Rating of patients' difficulties in the implementation of the intervention (Did the
patients perform the interventions? How often? Was it difficult to the patients?)
- Observations sheet: height, weight, BMI, hand grip strength, circumference of arm
muscle, circumference of calf
- The results of laboratory tests: sodium , albumins, lymphocytes, LDL cholesterol, C
reactive proteins, glomerular filtration rate, fasting glucose, thyroid hormones
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Active, not recruiting |
NCT04992286 -
Detection, Evaluation and Monitoring of Frailties in the Elderly (FRAGING)
|
N/A | |
Enrolling by invitation |
NCT05009706 -
Self-care in Older Frail Persons With Heart Failure Intervention
|
N/A | |
Recruiting |
NCT05529147 -
The Effects of Medication Induced Blood Pressure Reduction on Cerebral Hemodynamics in Hypertensive Frail Elderly
|
||
Recruiting |
NCT04444544 -
Quality of Life and High-Risk Abdominal Cancer Surgery
|
||
Completed |
NCT04061785 -
Impact of Skills Acquired Through Judo Training on Risk Factors for Falling in Elderly Men and Women
|
N/A | |
Completed |
NCT04140890 -
Supporting Habit Formation to Attenuate Prefrailty in Elders: Pilot Study
|
N/A | |
Recruiting |
NCT03141866 -
Seated Physical Activity in Ageing
|
N/A | |
Completed |
NCT04888884 -
Loss of Independence - a Rapid Alternative to Frailty Screening in a Swedish ED Setting
|
||
Recruiting |
NCT04145726 -
Frailty In Thoracic Surgery for Esophageal Cancer
|
||
Recruiting |
NCT04717869 -
Identifying Modifiable PAtient Centered Therapeutics (IMPACT) Frailty
|
||
Not yet recruiting |
NCT06022666 -
PATH Program for for Severely Frail or Cognitively Impaired Patients Scheduled for Cancer Surgery.
|
N/A | |
Not yet recruiting |
NCT06042244 -
Multimodal Exercise Training to Reduce Frailty in People With Multiple Sclerosis
|
N/A | |
Not yet recruiting |
NCT04514536 -
Evaluation of a Health Monitoring Platform for Elderly in Home Care Context
|
N/A | |
Completed |
NCT01126723 -
Effects of Tai Chi on Frailty in Elderly Adults
|
N/A | |
Completed |
NCT00183040 -
HORMA: Hormonal Regulators of Muscle and Metabolism in Aging
|
Phase 2 | |
Recruiting |
NCT05961319 -
Smart Home Technologies for Assessing and Monitoring Frailty in Older Adults
|
||
Enrolling by invitation |
NCT05047731 -
Antihypertensive Deprescribing in Long-term Care
|
N/A | |
Completed |
NCT04956705 -
Vitamin D and Calcium Supplementation at Danish Nursing Homes
|
N/A | |
Recruiting |
NCT03824106 -
Frailty Rehabilitation
|
Phase 4 | |
Recruiting |
NCT04518423 -
Prevalence, Determinants and Natural History of Frailty and Pre-frailty in Elderly People
|