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Locally Applied Antibiotics for Infection Prophylaxis in Treatment of Open Fractures

Fractures, Open Clinical Trial

Official title:
Locally Applied Antibiotics for Infection Prophylaxis in Treatment of Open Fractures

Clinical Trial Summary

The primary objective of this study is to investigate the effectiveness of local antibiotic versus placebo in the prevention of infections in open fractures. The study will assess whether local treatment of open fractures with the antibiotic tobramycin (in addition to standard systemic antibiotics) will decrease the risk and rate of infection, and rate of re-operation. This will be studied using a randomized controlled clinical trial design in adult population of age 18-70 years who present with open fractures. About 133 subjects will be recruited in this study at UVA.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03705962
Study type Interventional
Source University of Virginia
Contact
Status Terminated
Phase Phase 3
Start date July 2015
Completion date March 7, 2019
View Details
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