Fatigue Clinical Trial
Official title:
The Effect of BioSteel Sports Drink Supplementation on Muscular Fatigue, Cognitive Function, and Recovery Following Sprint Interval Exercise
BioSteel Sports Drink (BSD), a proprietary blend of branched chain amino acids, taurine, and B vitamins, has increased its popularity among professional and amateur athletes. BioSteel claims that BSD attenuates muscular and mental fatigue, and enhances recovery when consumed before and during intense exercise. To date, the efficacy of BSD on attenuating muscular and mental fatigue, and enhancing recovery during repeated bouts of intense exercise is unknown. In a blind crossover study, participants will be subjected to sprint interval exercise followed by muscular and cognitive function testing under two conditions: BSD and isoenergetic control.
Status | Not yet recruiting |
Enrollment | 15 |
Est. completion date | December 2014 |
Est. primary completion date | December 2014 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Male |
Age group | 18 Years to 35 Years |
Eligibility |
Inclusion Criteria: - Healthy, exercise-trained males aged 18-35 years. Participants can not have consumed BioSteel Sports Drink before. To ensure participants are highly trained, they must achieve the 2013 National Hockey League Combine average scores or better on 5 exercise tests (150 lb bench press, 8 lb sitting medicine ball toss, standing long jump, vertical jump and maximal oxygen consumption test on cycle ergometer). Women will be studied subsequently to asses andy gender differences. Exclusion Criteria: - Have symptoms or take medication for respiratory, cardiovascular, metabolic, neuromuscular disease. - Been diagnosed with a cognitive impairment and/or learning disability - Injury limiting exercise ability - Use of any medications with side effects of dizziness, lack of motor control, or slowed reaction time - Use of any other dietary supplements (excluding protein powder) - History of concussion/head injuries - Have an excessive alcohol intake (>2 drinks/day) - Smoker |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator)
Country | Name | City | State |
---|---|---|---|
Canada | 3M CTR - Rm 2235 | London | Ontario |
Lead Sponsor | Collaborator |
---|---|
University of Western Ontario, Canada |
Canada,
Blomstrand E, Hassmén P, Ek S, Ekblom B, Newsholme EA. Influence of ingesting a solution of branched-chain amino acids on perceived exertion during exercise. Acta Physiol Scand. 1997 Jan;159(1):41-9. — View Citation
Blomstrand E, Hassmén P, Ekblom B, Newsholme EA. Administration of branched-chain amino acids during sustained exercise--effects on performance and on plasma concentration of some amino acids. Eur J Appl Physiol Occup Physiol. 1991;63(2):83-8. — View Citation
Greer BK, White JP, Arguello EM, Haymes EM. Branched-chain amino acid supplementation lowers perceived exertion but does not affect performance in untrained males. J Strength Cond Res. 2011 Feb;25(2):539-44. doi: 10.1519/JSC.0b013e3181bf443a. — View Citation
Madsen K, MacLean DA, Kiens B, Christensen D. Effects of glucose, glucose plus branched-chain amino acids, or placebo on bike performance over 100 km. J Appl Physiol (1985). 1996 Dec;81(6):2644-50. — View Citation
Noble BJ, Borg GA, Jacobs I, Ceci R, Kaiser P. A category-ratio perceived exertion scale: relationship to blood and muscle lactates and heart rate. Med Sci Sports Exerc. 1983;15(6):523-8. — View Citation
van Hall G, Raaymakers JS, Saris WH, Wagenmakers AJ. Ingestion of branched-chain amino acids and tryptophan during sustained exercise in man: failure to affect performance. J Physiol. 1995 Aug 1;486 ( Pt 3):789-94. — View Citation
Watson P, Shirreffs SM, Maughan RJ. The effect of acute branched-chain amino acid supplementation on prolonged exercise capacity in a warm environment. Eur J Appl Physiol. 2004 Dec;93(3):306-14. — View Citation
Yatabe Y, Miyakawa S, Miyazaki T, Matsuzaki Y, Ochiai N. Effects of taurine administration in rat skeletal muscles on exercise. J Orthop Sci. 2003;8(3):415-9. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change from baseline in Muscular Power | Wingate test: Will be conducted using a cycle ergometer which electronically measures power (average, peak and decline). Resistance will be equal to 10% of subject body mass in kg. | Baseline and following each trial (1 day). | No |
Secondary | Change from baseline in Executive Function via Modified Stroop Test | Modified Stroop test- a measurement of attentional fatigue and executive function, will be scored based on error rate and mean response time (Kane & Kay, 1992). | Baseline and after each trial (1 day). | No |
Secondary | Change from baseline in anaerobic muscular power via Sitting Medicine Ball Toss | Sitting medicine ball toss using a standard 4kg medicine ball. Where the ball first lands will be measured as the total distance (recorded in cm.) | Baseline and after each trial (1 day). | No |
Secondary | Change from baseline in anaerobic muscular power via Standing Long Jump | Standing long jump will be conducted from a standing start with feet together. The distance from the jumping line to the individuals heels will recorded as the total distance (recorded in cm.) | Baseline and after each trial (1 day). | No |
Secondary | Change from baseline in anaerobic muscular power via Vertical Jump | Vertical jump will be conducted from a standing start. Without a pre-step individual will jump as a high as possible. Measurement is to the nearest cm. | Baseline and after each trial (1 day). | No |
Secondary | Change from baseline in muscular endurance via Bench Press | Bench press repetitions of 150 lbs (including the barbell) will be performed at a rate of 25 repetitions per minute. | Baseline and after each trial (1 day). | No |
Secondary | Change from baseline in speed of processing via Trail Making Test Part B | Trail Making Test Part B- a measurement of visual attention and speed of processing, will be scored on total time to completion (Sanchez-Cubillo et al., 2009). | Baseline and after each trial (1 day). | No |
Secondary | Change from baseline in subjective feeling of exertion via Rating of Perceived Exertion | Ratings of perceived exertion: Will be assessed after each sprint interval trial and at the conclusion of muscular endurance and power testing via a Borg Scale (Noble et al., 1983). | Baseline and after each trial (1 day) | No |
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