End Stage Renal Disease Clinical Trial
Official title:
Acute Brain Volume Changes in Haemodialysis: Comparison of Low Flux Haemodialysis With Pre-dilution Haemodiafiltration
The proposed controlled, randomized study aims to compare pre-dilution hemodiafiltration
(HDF) and low flux hemodialysis (HD) regarding acute changes in the brain.
The study consist of two examination days placed one week apart. 12 HD patients will be
recruited to the study. The patients will be randomly placed in two groups: Pre-dilution
hemodiafiltration during the first examination and low flux hemodialysis during the second
day or vice versa.
Brain Magnetic Resonance Imaging (MRI) will be obtained before and after both treatments.
The MRI-data will later be processed to estimate brain volume changes during the two types
of treatment.
n/a
Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Treatment
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