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Esophagitis clinical trials

View clinical trials related to Esophagitis.

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NCT ID: NCT02227836 Completed - Clinical trials for Eosinophilic Esophagitis

Value of Patch Testing in Direct Diet Therapy for Eosinophilic Esophagitis

EoE
Start date: August 2014
Phase: N/A
Study type: Interventional

This study is being done to see if allergy patch testing (APT) can help predict effective dietary therapy in patients with eosinophilic esophagitis.

NCT ID: NCT02204150 Completed - Clinical trials for Eosinophilic Esophagitis

Study to Image the Esophagus Using the OFDI Capsule

Start date: February 2012
Phase: N/A
Study type: Interventional

The main purpose of this research is to test the feasibility and tolerability of the tethered capsule Optical Frequency Domain Imaging (OFDI)

NCT ID: NCT02190513 Completed - Celiac Disease Clinical Trials

Prevalence of Eosinophilic Esophagitis in Children With Celiac Disease

Start date: February 2011
Phase: N/A
Study type: Observational

Celiac disease (CD) and eosinophilic esophagitis (EE) are distinct diseases of the gastrointestinal tract with specific clinico-pathological characteristics. In recent years, in the literature, several children who underwent upper gastrointestinal endoscopy for suspected CD, which was confirmed histologically, were also found to have coexistent EE. There are reports of coexistent CD and EE. We would like to see the prevalence of EE in children with CD and the prevalence of CD in children with EE in our population, and to do so would like to review medical records. Our objectives are to determine if children with celiac disease have a high prevalence of eosinophilic esophagitis.and to determine if children with eosinophilic esophagitis have increased risk of developing celiac disease.

NCT ID: NCT02153398 Completed - Clinical trials for Zollinger-Ellison Syndrome

A Phase I/III Study of D961H 10 mg and 20 mg in Japanese Paediatric Patients With Gastrointestinal Acid Related Diseases

Start date: June 2014
Phase: Phase 3
Study type: Interventional

The objective of this study is to assess the safety, pharmacokinetics, pharmacodynamics and efficacy of repeated once daily oral administration of D961H 10 mg and D961H 20 mg in Japanese paediatric patients aged 1 to 14 years old who either have a diagnosis of or are suspected to have gastric ulcer (GU), duodenal ulcer (DU), anastomotic ulcer (AU), non-erosive reflux esophagitis disease (NERD), reflux esophagitis (RE) or Zollinger-Ellison syndrome.

NCT ID: NCT02141711 Completed - Clinical trials for Gastroesophageal Reflux Disease (GERD)

TAK-438 - Safety, Blood Levels & Effects of Repeated Doses

TAK-438_107
Start date: October 2008
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics of TAK-438 in healthy, non-Japanese men male subjects following a randomized, double blind, placebo controlled, sequential panel, multiple-dose schedule.

NCT ID: NCT02125851 Completed - Clinical trials for Eosinophilic Esophagitis

Comparison of Esophageal Clearance Times of Oral Budesonide Preparations

Start date: January 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if a xanthan gum or honey based budesonide slurry exhibit comparable mucosal contact time to a budesonide/sucralose slurry in healthy adult subjects.

NCT ID: NCT02100189 Completed - Weight Loss Clinical Trials

Esophageal Cytology With FISH in Detecting Esophageal Cancer

Start date: February 2014
Phase: N/A
Study type: Interventional

This clinical trial studies whether esophageal cytology plus fluorescence in situ hybridization (FISH) is equal to or better than esophago-gastro-duodenoscopy (EGD) or upper endoscopy for the early detection of esophageal cancer. Genes are the units of deoxyribonucleic acid (DNA) the chemical structure carrying genetic information that determine many human characteristics. Certain genes in cancer cells may determine how the tumor grows or spreads and how it may respond to different drugs. Part of this study is to test those genes in esophageal cells using FISH.

NCT ID: NCT02098473 Completed - Clinical trials for Eosinophilic Esophagitis

Dose Ranging Study of RPC4046 in Eosinophilic Esophagitis

Start date: August 31, 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the effective dose(s) of RPC4046 in the treatment of Eosinophilic Esophagitis (EoE). This trial consists of two phases: 16 weeks of double-blind treatment and 52 weeks of open-label extension.

NCT ID: NCT02096458 Completed - Clinical trials for Gastroesophageal Reflux Disease

Sensory Evaluation of Dexlansoprazole Delayed-Release Orally Disintegrating Tablets

Start date: February 2014
Phase: Phase 1
Study type: Interventional

The purpose of this study is to measure the in-vivo disintegration time of a single dexlansoprazole delayed-release orally disintegrating (OD) tablet.

NCT ID: NCT02072590 Completed - Celiac Disease Clinical Trials

Improved Diagnostics of Celiac Disease in Children

Start date: August 2011
Phase:
Study type: Observational

The main purpose of this study is to improve the diagnostics of celiac disease and reduce the need for invasive endoscopic studies in children. Further, the investigators aim to investigate the natural history and risk of complications in children with celiac disease or gluten sensitivity and to create a large scientific database.