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Erectile Dysfunction clinical trials

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NCT ID: NCT04416802 Recruiting - Clinical trials for Erectile Dysfunction

Combined Treatment of Platelet-rich Plasma (PRP) and Low-intensity Extracorporeal Shockwave Therapy (Li-ESWT) on Erectile Dysfunction (ED)

Start date: December 28, 2020
Phase: N/A
Study type: Interventional

The purpose of this clinical study is mainly to use platelet-rich plasma combined with low-intensity extracorporeal shockwave therapy to treat patients with erectile dysfunction and observe the improvement results.

NCT ID: NCT04399057 Recruiting - Clinical trials for Erectile Dysfunction

Shear Wave Elastography New Ultrasound Approach for the Erectile Dysfunction

Start date: May 13, 2020
Phase:
Study type: Observational

the study proposes the use of a new non-invasive ultrasound method for the diagnosis of erectile dysfunction. in particular, the shear Wave elastosonosgraphy of the corpora cavernosa will be used. this last method quantitatively measures the rigidity of the analyzed tissues.

NCT ID: NCT04349059 Recruiting - Clinical trials for Erectile Dysfunction

The Impact of Dietary Pattern on Erectile Function

ERECTION
Start date: October 30, 2023
Phase: N/A
Study type: Interventional

The goal of this study is to determine whether erectile function is impacted by dietary patterns in healthy men with normal erectile function.

NCT ID: NCT04345965 Recruiting - Clinical trials for Erectile Dysfunction

Sirolimus Eluting Balloon Utilization for Treatment of Vasculogenic Erectile Dysfunction

SUASION
Start date: September 1, 2019
Phase:
Study type: Observational

Brief Summary: Background and pathophysiology: Erectile dysfunction (ED) is defined as the recurrent inability to achieve and maintain an erection satisfactory for sexual intercourse. ED is not in itself a "serious" disease, but its impact on quality of life is extremely important, affecting the family and interpersonal relationships. Male erection is a complex mechanism that involves neuro-vascular tissue responses with several phases including arterial dilatation, smooth muscle cells relaxation and ultimately veno-occlusive activation. Vasculogenic erectile dysfunction can be divided in arteriogenic (when there is insufficiency of arterial component of erection due to atherosclerotic plaque encroachment of the penile arteries) or venogenic (where there is insufficiency of the venous component of erection for venous endoleak) Standard treatment Erectile dysfunction is commonly treated by oral phosphodiesterase-5-inhibitor (PDE5i) administration. However, up to 50% of men have a suboptimal response to PDE5-i therapy with the need of additional therapies. New treatment Only recently several studies have been published on percutaneous treatment of ED using plain old balloon angioplasty (POBA), Drug eluting balloons (both paclitaxel and sirolimus, PEB and SES) and drug eluting stents (DES). Aim of the study: Evaluation of the safety and feasibility of sirolimus drug eluting balloon treatment in focal atherosclerotic lesions of the internal pudendal arteries among men with erectile dysfunction (ED) and a no response to phosphodiesterase-5 inhibitors.

NCT ID: NCT04341025 Recruiting - Clinical trials for Situational Erectile Dysfunction

Providing Insight Into and Mindfulness for Situational Erectile Dysfunction

PRIMED
Start date: April 14, 2020
Phase: N/A
Study type: Interventional

Erectile dysfunction (ED) is among the most common sexual dysfunctions experienced by men, affecting at least one third of men across the lifespan. Although pharmacological treatments are available, adherence to these treatments is poor, suggesting the need for integration of psychological interventions. This study will determine if a 6-session mindfulness-based psychosexual therapy (MBPST) group will be effective and feasible for men with situational ED. This study is adapted from a previously published 4-session MBPST protocol which was found to be beneficial for men with situational ED. Outcomes are measured using self-report questionnaires on sexual functioning/enjoyment, relationship satisfaction, and treatment acceptability.

NCT ID: NCT04219462 Recruiting - Clinical trials for Diabetes Mellitus, Type 2

Effect of ESWT on ED in Type 2 Diabetics

Start date: December 2, 2019
Phase: N/A
Study type: Interventional

Diabetes mellitus (DM) is known not only for its widespread prevalence, but also for its significant complications including cerebrovascular disease, coronary artery disease, renal failure, vision loss, and neuropathy. Of particular importance to sexual medicine, diabetes has also been strongly associated with erectile dysfunction (ED).ED is defined as the inability to obtain and/or maintain the erection firm enough to achieve a successful sexual intercourse on a regular basis. It is a more common condition in males with type 2 DM. In the field of sexual medicine numerous studies have shown that extracorporal shock wave therapy (ESWT) is safe, noninvasive, and, most importantly, an effective method for treating vascular ED

NCT ID: NCT04185441 Recruiting - Clinical trials for Erectile Dysfunction

Efficacy and Safety of Tanzânia Association in the Treatment of Erectile Dysfunction Associated With Benign Prostatic Hyperplasia

Start date: March 14, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of Tanzânia association in adults with erectile dysfunction associated with Benign Prostatic Hyperplasia.

NCT ID: NCT04172558 Recruiting - Clinical trials for Erectile Dysfunction

Intracavernous Injection of Botox 100 U for Treatment of PDE5Is Inconvenient Patients With ED

Start date: March 10, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

There is a new emerging concept that Botulinum Toxin Type A may have a potential role in treatment of erectile dysfunction with a longer duration of action. So, the investigators opted to perform this study to compare ICI of Botulinum Toxin Type A versus Trimix for treatment of ED.

NCT ID: NCT04116060 Recruiting - Clinical trials for Erectile Dysfunction

Dietary Nitrate and Erectile Dysfunction

Start date: February 17, 2020
Phase: N/A
Study type: Interventional

An expanding number of studies suggest a therapeutic role for nitrate and nitrite, most notably in treatment and prevention of cardiovascular disease including ischemia-reperfusion injury and hypertension. The nutritional aspects of these cardioprotective effects are particularly intriguing since nitrate is abundant in our everyday diet. Nitrate improves vascular functions in old adults and improves ischemia reperfusion injury in experimental models. Whether dietary nitrate improves erectile dysfunction is not known and will be investigated in the present study.

NCT ID: NCT04064671 Recruiting - Clinical trials for Erectile Dysfunction

ZEPHYR: A Study Evaluating Surgical Outcome After Implantation of the Zephyr ZSI 475 FTM Inflatable Penile Implant in the Neophallus After Female-to-male Sex Reassignment Surgery

Start date: September 19, 2017
Phase:
Study type: Observational

This study will look into the surgical outcome after implantation of the Zephyr ZSI 475 FTM in the neophallus.