Evaluation of Functional MRI and DTI (Imaging Techniques) in Children With Epilepsy and Focal Brain Lesions

Epilepsy Clinical Trial

Official title:

Advanced MR Imaging Evaluation Of Neurosurgical Candidates With Focal Abnormalities

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00229840
• Other study ID #: Functional MRI
• Status: Completed
• Phase: N/A
• First received: September 13, 2005
• Last updated: June 24, 2011
• Start date: February 2006
• Est. completion date: April 2008

Study information

• Verified date: June 2011
• Source: Children's Healthcare of Atlanta
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Food and Drug Administration
• Study type: Interventional

Clinical Trial Summary

This study is being done to look at the relationship between brain structure and brain function in patients with epilepsy or focal brain lesions (abnormal areas) that require surgery. This study will look at an imaging technique called magnetic resonance imaging (MRI) for looking at the brain. Specifically, the study will look at functional MRI, which is an imaging technique that can map brain function by taking pictures of the brain as it performs different tasks such as reading, thinking, or moving a body part and diffusion tensor imaging (DTI), which will look at brain structure. These types of imaging may help us learn more about different areas of the brain and how those areas of the brain are used in children with epilepsy. We plan to study 30 children with epilepsy.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 30
• Est. completion date: April 2008
• Est. primary completion date: April 2008
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 4 Years to 21 Years

Eligibility

Inclusion Criteria:

• children with intractable epilepsy

Exclusion Criteria:

• children requiring sedation for scanning

Study Design

Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

• Epilepsy

Intervention

Procedure:
• Functional MRI, Diffusion Tensor Imaging

Locations

Country	Name	City	State
United States	Children's Healthcare of Atlanta at Scottish Rite	Atlanta	Georgia

Sponsors (1)

Lead Sponsor	Collaborator
Children's Healthcare of Atlanta

Country where clinical trial is conducted

United States,