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Endoscopy clinical trials

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NCT ID: NCT00869440 Completed - Endoscopy Clinical Trials

Dose-Finding Safety Study Evaluating Remimazolam (CNS 7056) in Patients Undergoing Diagnostic Upper GI Endoscopy

Start date: March 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study was to assess the safety and efficacy of CNS 7056 as a procedural sedative at three dose levels compared to midazolam during a diagnostic upper GI endoscopy.

NCT ID: NCT00848146 Completed - Endoscopy Clinical Trials

NOTES-Assisted Laparoscopic Cholecystectomy Surgery

TAS-NOTES
Start date: February 2009
Phase: N/A
Study type: Interventional

Refinements in laparoscopic surgery, coupled with advancements in therapeutic flexible endoscopy, have set the stage for surgery to move to even less invasive techniques to treat conditions in the GI tract and peritoneal cavity. Natural orifice translumenal endoscopic surgery (NOTES) offers a means of reducing and ultimately eliminating the need for abdominal incisions to gain access to the peritoneal cavity. In NOTES, a flexible endoscope and accessory instruments are inserted through a natural body orifice and passed through the wall of an organ to reach the abdominal cavity. By reducing or eliminating the need for abdominal incisions, NOTES may provide a least invasive surgical option that can reduce pain, recovery time, complications, and systemic inflammatory response when compared to a laparoscopic surgical approach. In this study, we propose to use the NOTES technique to eliminate the need for a 1.5-2.5 cm umbilical incision. Hypothesis 1: We hypothesize that a combined endoscopic and laparoscopic approach will be able to eliminate a 1.5 to 2.5 cm infraumbilical incision when performing a laparoscopic cholecystectomy. Hypothesis 2: Closure of the gastrotomy will be facilitated with the Ethicon TAS system.

NCT ID: NCT00813033 Completed - Endoscopy Clinical Trials

Use of a Patient Decision Aid for Gastrologic Endoscopy in a Pediatric Setting

Start date: December 2008
Phase: N/A
Study type: Interventional

Parents need understandable information in order to make appropriate choices for their child's health care. This is especially true when making decisions about invasive medical procedures. Parents need to understand what will happen, the risks involved, how these risks will be managed and what other options they have before they can decide what is best for their child. The present proposal involves the creation of a novel patient decision aid about the gastro endoscopy procedure, called a "scope." The purpose of the aid is to provide parents with information so they are able to discuss the options with their child's health care providers.

NCT ID: NCT00732212 Completed - Endoscopy Clinical Trials

Doppler Ultrasound Probe for Blood Flow Detection in Severe Upper Gastrointestinal Hemorrhage

Start date: February 18, 2009
Phase: N/A
Study type: Interventional

The main purposes of this study are to compare clinical outcomes of two groups of patients with similar medical conditions (one with non-variceal upper gastrointestinal (UGI) lesions such as ulcers and another group with varices or portal hypertensive lesions) who are treated either with current standard visually guided endoscopic treatment according to stigmata of hemorrhage or with endoscopic Doppler endoscopic ultrasound probe (DEP) monitoring of blood flow in the lesion.

NCT ID: NCT00709046 Recruiting - Bleeding Clinical Trials

High Dose Versus Standard Dose Proton Pump Inhibitor (PPI) in High-risk Bleeding Peptic Ulcers After Combined Endoscopic Treatment

Start date: January 2008
Phase: N/A
Study type: Interventional

The study was designed to evaluate the efficacy an adjuvant use of standard dose or high dose of proton pump inhibitor after combined endoscopic hemostasis therapy.

NCT ID: NCT00677794 Completed - Endoscopy Clinical Trials

Small Bowel Cleansing Prior to Video Capsule Endoscopy Examination

Start date: March 2008
Phase: Phase 4
Study type: Interventional

There remains debate regarding whether small bowel cleansing is required prior to video capsule endoscopy, and if so, which method is best. This study prospectively tests cleansing with no preparation, preparation with picosalax, and preparation with polyethylene glycol.

NCT ID: NCT00671177 Completed - Colonoscopy Clinical Trials

Clinical Evaluation of Water Immersion Colonoscopy Insertion Technique

Start date: September 2007
Phase: N/A
Study type: Interventional

Recent studies indicate that infusing 300 milliliters of water (in lieu of air) into the rectum and left colon through the colonoscope as it is being inserted during a colonoscopy examination can allow easier endoscope advancement. This method may prevent stretching of the colon, and ultimately reduce pain induced during colonoscopy. Improvements in patient comfort and cooperation, may increase the efficiency and success rate of complete colonoscopy. The purpose of the study is to test the efficacy of the water immersion technique in patients colonoscopy.

NCT ID: NCT00636428 Completed - Endoscopy Clinical Trials

Clinical Trial of Oral Midazolam in Pediatric Endoscopy

Start date: March 2007
Phase: Phase 4
Study type: Interventional

The objective of our study was to compare the safety and efficacy of oral midazolam during pediatric endoscopy.

NCT ID: NCT00614159 Completed - Endoscopy Clinical Trials

Ketamine Compared to Propofol for Pediatric GI Endoscopy

Start date: October 2007
Phase: N/A
Study type: Observational

Elective outpatient endoscopy for children can be safely performed under general anesthesia with either propofol (1) or ketamine (2) infusions. Both infusions have an advantage over general anesthesia with volatile agents because they do not require intubation. The goal of both infusions is to have the patient breath spontaneously without reacting to the endoscopy which is a noxious stimulus. Patient movement, stridor and vomiting are can interrupt the procedure and increase overall OR time. Propofol also carries the added risk of causing apnea. This side effect is not commonly seen with Ketamine. Our hypothesis is that Ketamine's profile makes it a superior drug to Propofol for elective outpatient endoscopy because of reduced profound intra-operative interruptions and faster recovery time. We plan a study of pediatric patients ages 1 to 10 years old undergoing elective outpatient endoscopy. The patients will be randomized to receiving either a Ketamine or Propofol infusion, and the intra-operative interruptions will be documented by the anesthesiologist. The Post Anesthetic Care Unit (PACU) time to recovery will be monitored and recorded by a third party.

NCT ID: NCT00173368 Completed - Endoscopy Clinical Trials

Study of Endoscopic Sphincterotomy With Needle Knife Papillotome in Patients of Ampullary Impacted Stone

Start date: January 2003
Phase: N/A
Study type: Observational

Using a needle knife papillotome by an experienced endoscopist, endoscopic sphincterotomies were performed in difficult cannulation cases. In a prospectively collected database, we investigate the complications of those with ampullary impacted stone.