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NCT05267249 Clinical Trial

Revascularisation of Autotransplanted Teeth

Endodontic Disease Clinical Trial

Official title:
Revascularisation of Autotransplanted Teeth - Retrospective Analysis of a Novel Technique

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05267249
Other study ID # ResectTX
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date August 6, 2021
Est. completion date February 15, 2022

Study information
Verified date February 2022
Source Medical University of Graz
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Retrospective Analysis of a Study cohort that experienced autotransplantation of mature teeth with simultaneous root end resection Note: The study was registered on Clinicaltrials.gov after termination of study.

Recruitment information / eligibility
Status Completed
Enrollment 16
Est. completion date February 15, 2022
Est. primary completion date February 1, 2022
Accepts healthy volunteers No
Gender All
Age group 12 Years to 70 Years
Eligibility Inclusion Criteria: - Male and female consenting and judicious young people and adults - Written consent of the participant and, if applicable, of the legal guardian after education - Planned tooth transplantation with advanced or completed root growth Exclusion Criteria: - Contraindications for magnetic resonance imaging (MRI): (pronounced metal restorations, running orthodontics with metal, fixed appliance in the target jaw) - Current or past antiresorptive therapy with bisphosphonates - Further anamnestic general or local risk situation, among others: Anti-angiogenic therapy, History of local radiation therapy, severe coagulation disorder, unadjusted diabetes mellitus, malignant diseases - Acute gingivitis or advanced periodontitis - Participation in an ongoing drug trial (various drugs may distort the result, such as bisphosphonates, cortisone, chemotherapeutics, angiogenesis inhibitors) - heavy smokers (> 10 per day) - Acute or chronic infections (osteomyelitis) at the surgical site - metabolic diseases (diabetes, hyperparathyroidism, osteomalacia) - Severe kidney dysfunction, severe liver disease - Patients with high-dose corticosteroid therapy - prolonged corticosteroid or radiotherapy in the oral cavity - autoimmune diseases - Pregnant or breastfeeding women

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• Autotransplantation and Apicoectomy
Autotransplantation of a mature teeth with simultaneous extra-oral root-end resectoin

Locations
Country Name City State
Austria Medical University of Graz Graz Styria

Sponsors (1)
Lead Sponsor Collaborator
Medical University of Graz

Country where clinical trial is conducted

Austria, 

References & Publications (1)

Jakse N, Ruckenstuhl M, Rugani P, Kirnbauer B, Sokolowski A, Ebeleseder K. Influence of Extraoral Apicoectomy on Revascularization of an Autotransplanted Tooth: A Case Report. J Endod. 2018 Aug;44(8):1298-1302. doi: 10.1016/j.joen.2018.04.016. Epub 2018 Jun 20. — View Citation

Outcome
Type Measure Description Time frame Safety issue
Primary Survival Tooth survival 1 year
Secondary Revascularisation Occurrence of Revascularisation 1 year
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