Clinical Trials Logo
  1. Home
  2. Drug Use Disorders
  3. NCT03373240

Targeting Self-regulatory Deficits Through Cognitive Remediation Intervention

Drug Use Disorders Clinical Trial

Official title:
Targeting Self-regulatory Deficits Through Cognitive Remediation Intervention

Clinical Trial Summary

We are proposing a small randomized clinical trial in which 100 substance users will complete the existing Psychotherapy Development Center (PDC) pretreatment assessment battery as well as a novel battery of assays to evaluate cognitive-affective functioning. After completing pretreatment assessments, participants will be randomized to either a (1) cognitive remediation program (training tasks) specifically designed to address cognitive-affective dysregulation or (2) control tasks (verbal fluency tasks). Tasks will be completed twice per week for 4 weeks, after which assessment batteries will be repeated. Finally, we will evaluate real-world behavior and the durability of the training via a one-month follow-up, which will include assessment of substance use as well as the cognitive-affective battery.

Clinical Trial Description

Participants will be 100 individuals (aged 18 to 50) enrolled in outpatient (non- methadone/buprenorphine) treatment for any substance use disorder (other than PCP) at the Substance Abuse Treatment Unit in New Haven. As the goal of this project is to develop interventions that address self-regulation across multiple disorders, we will recruit individuals who have a range of substance use disorders and levels of severity. Our primary Specific Aim will be to evaluate the efficacy of the cognitive-remediation program relative to the control condition control on the indicators of cognitive-affective functioning and substance use, testing the hypothesis that individuals randomized to the cognitive remediation program will demonstrate improved functioning on the cognitive-affective battery as well as reduced real-world substance abuse. We will also explore potential moderators of response to the training, including baseline measures of cognitive-affective function. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03373240
Study type Interventional
Source Yale University
Contact
Status Completed
Phase N/A
Start date January 22, 2018
Completion date October 17, 2019
View Details
See also
  Status Clinical Trial Phase
Completed NCT02224508 - Evaluation of a Health Plan Initiative to Mitigate Chronic Opioid Therapy Risks N/A
Completed NCT01413529 - HEART to HAART: Smartphone Intervention to Improve HAART Adherence for Drug Users Phase 2
Completed NCT01141920 - Comparison of Two Counseling Induction Strategies N/A
Completed NCT00237822 - Increasing Treatment Adherence in Co-Occurring Psychiatric and Drug Use Disorders Phase 2
Completed NCT03678051 - CBT4CBT for Women in Residential Treatment for Substance Use Disorders N/A
Recruiting NCT04003948 - Preliminary Efficacy and Safety of Ibogaine in the Treatment of Methadone Detoxification Phase 2
Active, not recruiting NCT03713983 - Treatment Outcomes Among Patients With Prescription Narcotic Drug Use Disorder
Active, not recruiting NCT02601495 - Latent Structure of Multi-level Assessments and Predictors of Outcomes for Women in Recovery
Recruiting NCT05534568 - The Oklahoma Parent-Child Assistance Program N/A
Active, not recruiting NCT04907045 - An Initial Study of the Implementation of Digital Therapeutics for Substance Use Disorders in Primary Care N/A
Not yet recruiting NCT06317987 - Addressing Barriers to Care for Substance Use Disorder Pilot Study N/A
Completed NCT04268173 - Community-Based, Client-Centered Prevention Homes to Address the Rural Opioid Epidemic- Aim 3 Phase 3
Active, not recruiting NCT06249542 - Implementing Screening for Cannabis and Other Drug Use Disorders in Primary Care: Impact on Diagnosis and Treatment N/A
Completed NCT02450240 - Latent Structure of Multi-level Assessments and Predictors of Outcomes in Psychiatric Disorders
Recruiting NCT03069118 - 90-Day Online Substance Use Program N/A
Active, not recruiting NCT05160233 - Digital Treatments for Opioids and Other Substance Use Disorders in Primary Care N/A
Completed NCT03451344 - A Electronic System to Improve Recovery Outcomes in Patients With Drug Use Disorder N/A
Completed NCT00798538 - Integration of Buprenorphine Into HIV Clinical Settings - Primary Care Model (PCM) Phase 4
Completed NCT03684252 - Reducing Self-stigma in Persons With HIV and Drug Use Disorders in Primary Health Care Settings N/A
Not yet recruiting NCT06163651 - Evaluating a One-Year Version of the Parent-Child Assistance Program N/A