Distal Radius Fracture Clinical Trial
Official title:
A Clinical Trial for the Surgical Treatment of Elderly Distal Radius Fractures. The Wrist and Radius Injury Surgical Trial (WRIST)
In the United States, over 300,000 individuals over age 65 suffer from distal radius
fractures (DRFs) each year. Despite the frequency of this injury and over 200 years of
experience treating DRFs, management of elderly DRFs is still controversial. Close reduction
and casting is a nonsurgical technique that is frequently used, but osteoporotic fractures,
common in the elderly, often collapse and displace. The three currently applied surgical
techniques are close reduction and percutaneous pinning, external fixation with or without
percutaneous pinning, and internal fixation with volar locking plating. Preliminary evidence
indicates that locking plate fixation can permit elderly patients to move their hands and
wrists much sooner in order to return to self-care activities more quickly. Although these
outcomes are promising, there is no randomized controlled clinical trial to demonstrate that
the more invasive, and perhaps more costly, plating technique is superior to the other
simpler approaches.
The specific aim of this 24-center randomized controlled trial is to compare outcomes of
these three surgical techniques in treating unstable DRFs in the elderly. The secondary aim
is to follow a cohort of elderly patients who choose not to have surgery to evaluate outcomes
following treatment by close reduction and casting alone. This clinical trial is the most
ambitious study in hand surgery by assembling most of the leading centers in North America to
collect evidence-based data to guide future treatment of this prevalent injury in the growing
elderly population.
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Status | Clinical Trial | Phase | |
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Recruiting |
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|
N/A | |
Completed |
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Usefulness of Intraoperative Ultrasound in a Volar Plate Distal Radius Fixation
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||
Completed |
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Effects of Early Manual Therapy on Functional Outcomes After Volar Plating of Distal Radius Fractures
|
N/A | |
Completed |
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Evaluating Validity of Ultrasonography in Determining Distal Radius Fracture Reduction
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Phase 2 | |
Completed |
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Short-Arm Casting Effective in Type A2 Fractures in the Distal Radius
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N/A | |
Completed |
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Volar Locked Plating Versus Bridging External Fixation
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N/A | |
Not yet recruiting |
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Spanning Bridged Plate in Comminuted Distal Radius Fractures
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||
Recruiting |
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Quantitative and Clinical Assessment of Flexor Tendon Gliding Following Application of a Bioresorbable Hydrogel: A Prospective, Randomized Study in Patients Undergoing Distal Radius Fracture Repair
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N/A | |
Completed |
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Distraction Osteogenesis for Distal Radius Fractures vs. Volar Plating
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N/A | |
Not yet recruiting |
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Occupational Therapy Pre-operative Education in the Orthopedic Hand Setting
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N/A | |
Terminated |
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Single Shot vs Catheter Infraclavicular Brachial Plexus Block After Distal Radius Fracture Repair
|
N/A | |
Completed |
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Cortical Comminution and Intra-articular Involvement in Distal Radius Fractures Can Predict Radiological Outcome. A Prospective Multicenter Study
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N/A | |
Completed |
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Radiological vs Clinical Outcome in DRF
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N/A | |
Active, not recruiting |
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Bier's Block Versus Systemic Analgesia
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Phase 2 | |
Completed |
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Manual Dexterity in Ulnar Styloid Fracture Patients
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N/A | |
Completed |
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N/A | |
Recruiting |
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Graded Motor Imagery for Women at Risk for Developing Type I CRPS Following Closed Treatment of Distal Radius Fractures
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Completed |
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Well-arm Exercise in Distal Radius Fractures
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N/A | |
Completed |
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|
N/A |