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Topical Application of Latanoprost in Diabetic Retinopathy — Latano-2  

Diabetic Retinopathy Clinical Trial

Official title:
Topical Application of Latanoprost in Diabetic Retinopathy

Clinical Trial Summary

Randomized double-blinded two-year intervention study with topical application of latanoprost or placebo eye drops in patients with diabetic retinopathy.

Clinical Trial Description

The primary objective is to study if a sustained contraction of pathologically dilated retinal arterioles can be obtained. Retinal arteriolar diameter and the diameter response to increased blood pressure is studied using the Dynamic Vessel Analyzer (Imedos, Germany.

The secondary objective is to study whether the intervention can halt the development of diabetic retinopathy, which is assessed by optical coherence tomography (OCT) scanning and fundus photography. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01225653
Study type Interventional
Source University of Aarhus
Contact
Status Completed
Phase Phase 4
Start date November 2010
Completion date December 2014
View Details
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