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Evaluation of Blood-retinal Barrier Functional Alterations by Optical Coherence Tomography — CNTM025A OCT  

Diabetic Retinopathy Clinical Trial

Official title:
Evaluation of Blood-retinal Barrier Functional Alterations by Optical Coherence Tomography

Clinical Trial Summary

The purpose of this study is to identify alterations of the blood-retinal barrier (BRB) in diabetic retinas using a novel non-invasive approach based on the Fourier domain high-definition optical coherence tomograph (OCT).

Clinical Trial Description

Type 2 diabetic patients with nonproliferative diabetic retinopathy (NPDR) (study population) and healthy volunteers (control population).

Inclusion Criteria:

Age over 18 years; type-2 diabetes; NPDR levels 10, 20 and 35/47 (ETDRS severity scale); and an area of retinal leakage of at least 25% of the RLA map (macular area).

Exclusion Criteria:

Presence of media opacity; vitreous syneresis or posterior vitreous detachment, and; previous photocoagulation treatments or any type of intraocular surgery or intravitreal medications; and other retinal pathologies. ;

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01220804
Study type Observational
Source Association for Innovation and Biomedical Research on Light and Image
Contact
Status Completed
Phase N/A
Start date November 2010
Completion date March 2013
View Details
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