A RCT to Compare the Effects of Two Wound Products on Biofilm Disruption

Status Terminated

Clinical Trial Summary

This study is a prospective comparative study to determine if an Iodine Gel (Iodosorb◊) is better than standard dressing (Solosite◊ gel) in disruption of biofilm (small microorganism bacteria similar to plaque on teeth) on the wound bed diabetic foot ulcers. ◊ Trademark of Smith & Nephew

Clinical Trial Description

IODOSORB gel is a cadexomer iodine product indicated for use in wet ulcers and wounds. As the use of IODOSORB has an anti-microbial effect and removes exudate continuously from the wound, a reduction in pain, odour, oedema, exudate, pus and debris, and microbial load including biofilm can be achieved, hence providing an environment conducive to the normal healing process. While evidence exists to support the use of IODOSORB in diabetic foot ulcers (DFUs) for the reduction of planktonic bacteria, little evidence exits for the effect of any topical therapy on non-planktonic or biofilm bacteria in-vivo. The aim of this study is to explore the effects of IODOSORB on biofilm in the wound, wound healing, and associated factors, such as odour, pain, and reduction of slough. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02181621
Study type	Interventional
Source	Smith & Nephew, Inc.
Contact
Status	Terminated
Phase	N/A
Start date	August 2014
Completion date	October 2015

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See also
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A RCT to Compare the Effects of Two Wound Products on Biofilm Disruption in DFUs

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms