The Correlation Between HbA1c and Mean Blood Glucose in Patients With Diabetes and Renal Failure

Diabetes Clinical Trial

Official title:

The Correlation Between HbA1c and Mean Blood Glucose in Patients With Diabetes and Renal Failure

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT01937858
• Other study ID #: RC08/107/A
• Status: Terminated
• Start date: July 2012
• Est. completion date: July 2016

Study information

• Verified date: February 2020
• Source: King Abdullah International Medical Research Center
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The value of HbA1c as a tool to determine glycemic control in patients with diabetes and renal failure has not been well studied, the same accepted normal ranges for HbA1c are applied to all patients with diabetes regardless of their renal function. We would like to evaluate the use of HbA1c as a tool of assessing long term glycemic control in this subgroup of patients with diabetes and evaluate the effect of dialysis on HbA1c

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 50
• Est. completion date: July 2016
• Est. primary completion date: March 2016
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

All patients >18 years of age with type 1 or 2 diabetes who show competence in home glucose monitoring and are willing to commit to doing the testing

Exclusion Criteria:

• Pregnancy

• Having received a blood transfusion with in the preceding three months

• Known to have any hereditary or hemolytic anemia

• On a medication known to interfere with HbA1c assay (opiates, acetaminophen, vitamin C, vitamin E) - we will allow patients to be on asprin as almost all patients with diabetes are on this drug.

• Having a blood hemoglobin <7 mg/dl

• Bilirubin level >20mg/dL or a triglyceride level > 250mg/dL

• Alcohol addiction

Related Conditions & MeSH terms

• Diabetes
• Diabetes Mellitus
• Renal Failure
• Renal Insufficiency

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Reem Mohammad Alamoudi

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Correlation	The quantitative correlation between mean blood glucose and HbA1c in patients with diabetes and renal failure	three months