Diabetes Mellitus, Type 2 Clinical Trial
Official title:
Confronting Unequal Eye Care in Pennsylvania
Pt. 1 Diabetic retinopathy is a common eye condition among diabetic adults and can lead to
severe vision impairment and even blindness. African Americans are more likely to have
vision loss from diabetic retinopathy due to a variety of factors, including cultural
barriers to care. The investigators aim to increase the rates of eye exams in diabetic
African American adults by providing culturally relevant home-based interventions. These
interventions will increase the knowledge about diabetes and the eyes and the awareness of
ocular risks due to diabetes.
206 African American adults, over the age of 65, with diabetes will be recruited from
primary care clinics at Thomas Jefferson and Temple University. Eligible patients who
consent to participate will have baseline information taken about medical and ocular
history, understanding of diabetes and a hemoglobin A1C level obtained. The subjects will
then be randomized to one of two treatment conditions: Behavioral Activation or Supportive
Therapy, each of which will be delivered over 4 sessions. Behavioral Activation will consist
of educational materials, referral assistance for eye clinics, and addressing patient
specific barriers to care. Supportive Therapy will consist of supportive but non-directional
interaction with the patient exploring the impact of aging and diabetes on the patient's
life. The investigators hypothesize that more patients who receive Behavioral Activation
will have a dilated fundus exam (the primary outcome variable), understand the risks of
diabetic complications and feel less depression then subjects who receive Supportive
Therapy.
An additional aim was added to this project, examining the effect of a telephone
intervention on eye care adherence and comparing the efficacy of the intervention to usual
care and automated telephone screenings.
Glaucoma is a group of chronic, neurodegenerative diseases of the optic nerve, which leads
to an increase in intraocular pressure, gradual changes in the visual field (VF), and
progressive vision loss. Glaucomatous vision loss is preventable with proper eye care,
including adherence to follow-up appointments and medications. Interventions that improve
appointment adherence have the potential to prevent more severe glaucomatous disease. The
primary purpose of this study is to determine the efficacy of a multifaceted intervention
system, which includes a customized letter and personal telephone outreach, in improving
appointment adherence in patients with glaucoma. In order to improve strategies to reduce
the rate of appointment non-adherence, shared characteristics of adherent versus
non-adherent patients with glaucoma will be identified and compared to patient
characteristics in the previous literature. A secondary goal of this study is to analyze the
cost-effectiveness of this multifaceted intervention on appointment adherence in patients
with glaucoma.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT05666479 -
CGM Monitoring in T2DM Patients Undergoing Orthopaedic Replacement Surgery
|
||
| Completed |
NCT05647083 -
The Effect of Massage on Diabetic Parameters
|
N/A | |
| Active, not recruiting |
NCT05661799 -
Persistence of Physical Activity in People With Type 2 Diabetes Over Time.
|
N/A | |
| Completed |
NCT03686722 -
Effect of Co-administration of Metformin and Daclatasvir on the Pharmacokinetis and Pharmacodynamics of Metformin
|
Phase 1 | |
| Completed |
NCT02836704 -
Comparison of Standard vs Higher Starting Dose of Insulin Glargine in Chinese Patients With Type 2 Diabetes (Glargine Starting Dose)
|
Phase 4 | |
| Completed |
NCT01819129 -
Efficacy and Safety of FIAsp Compared to Insulin Aspart in Combination With Insulin Glargine and Metformin in Adults With Type 2 Diabetes
|
Phase 3 | |
| Completed |
NCT04562714 -
Impact of Flash Glucose Monitoring in People With Type 2 Diabetes Using Non-Insulin Antihyperglycemic Therapy
|
N/A | |
| Completed |
NCT02009488 -
Treatment Differences Between Canagliflozin and Placebo in Insulin Secretion in Subjects With Type 2 Diabetes Mellitus (T2DM)
|
Phase 1 | |
| Completed |
NCT05896319 -
Hyaluronic Acid Treatment of the Post-extraction Tooth Socket Healing in Subjects With Diabetes Mellitus Type 2
|
N/A | |
| Recruiting |
NCT05598203 -
Effect of Nutrition Education Groups in the Treatment of Patients With Type 2 Diabetes
|
N/A | |
| Completed |
NCT05046873 -
A Research Study Looking Into Blood Levels of Semaglutide and NNC0480-0389 When Given in the Same Injection or in Two Separate Injections in Healthy People
|
Phase 1 | |
| Completed |
NCT04030091 -
Pulsatile Insulin Infusion Therapy in Patients With Type 1 and Type 2 Diabetes Mellitus
|
Phase 4 | |
| Terminated |
NCT04090242 -
Impact of App Based Diabetes Training Program in Conjunction With the BD Nano Pen Needle in People With T2 Diabetes
|
N/A | |
| Completed |
NCT03604224 -
A Study to Observe Clinical Effectiveness of Canagliflozin 300 mg Containing Treatment Regimens in Indian Type 2 Diabetes Participants With BMI>25 kg/m^2, in Real World Clinical Setting
|
||
| Completed |
NCT03620357 -
Continuous Glucose Monitoring & Management In Type 2 Diabetes (T2D)
|
N/A | |
| Completed |
NCT01696266 -
An International Survey on Hypoglycaemia Among Insulin-treated Patients With Diabetes
|
||
| Completed |
NCT03620890 -
Detemir Versus NPH for Type 2 Diabetes Mellitus in Pregnancy
|
Phase 4 | |
| Withdrawn |
NCT05473286 -
A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Germany, as Part of Local Clinical Practice
|
||
| Not yet recruiting |
NCT05029804 -
Effect of Walking Exercise Training on Adherence to Disease Management and Metabolic Control in Diabetes
|
N/A | |
| Completed |
NCT04531631 -
Effects of Dorzagliatin on 1st Phase Insulin and Beta-cell Glucose Sensitivity in T2D and Monogenic Diabetes
|
Phase 2 |