Physical Exercise and Depressive Symptoms in Moderately or Severely Depressed Adults

Depressive Symptoms Clinical Trial

— EXIMOS  

Official title:

Do Moderately and Severely Depressed Individuals Derive the Same Psychological Benefits From a 10-weeks Long Aerobic Exercise Program ?

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05703776
• Other study ID #: JBPMM-1
• Status: Completed
• Phase: N/A
• Start date: January 19, 2022
• Est. completion date: May 1, 2022

Study information

• Verified date: January 2023
• Source: Je Bouge Pour Mon Moral
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study is a comparative trial comparing the time course of depressive symptoms between moderately and severely depressed participants over a 10-week long exercise program

Description:

Sixty depressed French adults (34 with symptoms of moderate intensity and 26 with symptoms of severe intensity as defined by the PHQ-9 cutting scores) voluntarily participated in our comparative trial.

A control group (waiting list) of n = 16 including 8 severely depressed and 8 moderately depressed participants received no physical exercise.

For the remaining 44 participants (26 with moderate-intensity depressive symptoms and 18 with high-intensity depressive symptoms), two weekly Nordic Walking sessions of 1h were performed for 10 consecutive weeks.

Depressive symptoms were assessed using standard self-report questionnaires at various time points: 1/ enrollment (using the PHQ-9), and then (2) just before the beginning of the exercise intervention (pre-intervention; using the BDI-II), 2/ at the end of Week 5 (mid-intervention; using the BDI-II), and 3/ the day following the end of the exercise program (post-intervention)

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: May 1, 2022
• Est. primary completion date: April 15, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• PHQ-9 (Kroenke et al., 2001) score of 10 or above

Exclusion Criteria:

• medical contraindication to moderate-intensity aerobic exercise

• inability to read French language

Related Conditions & MeSH terms

• Depression
• Depressive Symptoms

Intervention

Behavioral:
• Nordic Walking
Nordic Walking (NW) is an aerobic physical activity where regular walking is enhanced by the addition of the active use of specifically designed NW poles. The physical strain is distributed in a balanced way to various muscle groups of the whole body.

Locations

Country	Name	City	State
France	association JBPMM	Nancy

Sponsors (2)

Lead Sponsor	Collaborator
Je Bouge Pour Mon Moral	University Grenoble Alps

Country where clinical trial is conducted

France, 

References & Publications (2)

Beck AT, Steer RA, Brown GK. Beck Depression Inventory (2nd edition). San Antonio, TX: Hartcourt Brace, 1996.

Kroenke K, Spitzer RL. The PHQ-9: a new depression diagnostic and severity measure. Psychiatric Annals. 2002; 32: 509-521.

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	change in the intensity of depressive symptoms	self-evaluated intensity of depressive symptoms. Was obtained using the standard Beck Depression Inventory (BDI-II; Beck et al., 1996)	10 weeks