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Clinical Trial Summary

The purpose of this study is to examine the effects of sub-callosal cingulate (SCC) deep brain stimulation (DBS) in patients with treatment resistant depression (TRD).

The working hypotheses are that long pulse-width DBS applied to the SCC region will lead to improvements in TRD patients, and specific neuroimaging biomarkers will correlate with response to DBS; the functional recovery will be enhanced with concurrent cognitive behavioural therapy (CBT).


Clinical Trial Description

The aim is to collect data on prediction, optimization and augmentation of DBS for TRD and develop tools for DBS surgery. It is a biological pilot study designed to provide informative data for future work. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT01983904
Study type Interventional
Source University of Calgary
Contact
Status Completed
Phase N/A
Start date August 2013
Completion date March 2018

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