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ECT/Succinylcholine: Biochemical, Serum and Cardiovascular Changes

Depression Clinical Trial

Official title:
The Muscle Biochemical, Serum Potassium and Cardiovascular Changes After Succinylcholine in Patients Undergoing Electroconvulsive Therapy.

Clinical Trial Summary

This study will be conducted to determine the pharmacodynamics, cardiovascular and biochemical effects of succinylcholine when given during electroconvulsive therapy. (ECT). This is a single center, prospective, study in patients who will be receiving ECT as indicated and prescribed by their psychiatrist. The study will be performed twice on each patient, 48-72 hours apart during consecutively scheduled ECT procedures.

Clinical Trial Description

Patients will receive the anesthetic that is traditionally given which includes appropriate doses of succinylcholine. Serum potassium and creatinine phosphokinase (CK) levels will be determined pre and post anesthesia; serum and urine myoglobin will be determined post anesthesia. Vital signs data [i.e., heart rate (arrhythmias) and arterial blood pressure] will be compared pre and post anesthesia. In addition patients will be asked about the presence of muscle pain (myalgia) 1 hour before discharge from the recovery room and the following day post ECT. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00750906
Study type Observational
Source University of California, San Francisco
Contact
Status Terminated
Phase
Start date October 2008
Completion date April 30, 2015
View Details
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