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Dentoalveolar Abscess clinical trials

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NCT ID: NCT04684407 Recruiting - Clinical trials for Dentoalveolar Abscess

C-reactive Protein Levels in Acute Apical Abscess Due to Root Canal Infection

Start date: November 1, 2020
Phase: N/A
Study type: Interventional

C-reactive protein levels of patients with acute apical abscess are evaluated before and after root canal treatment

NCT ID: NCT03761264 Completed - Clinical trials for Dentoalveolar Abscess

Systemic and Local Antimicrobials in the Management of Dental Abscess in Children

Start date: September 18, 2018
Phase: Phase 2
Study type: Interventional

Dental infections originating in the teeth are routinely managed systemically with a course of oral antibiotics, while severe forms are managed with intravenous antibiotics. Dental infections can also be managed by removing the offending cause of the infection followed by placement of an intra-canal medication which acts as a local antimicrobial. Intra-canal medicaments are being used in clinical practice following root canal treatment. The investigators hypothesize that the effect of intra-canal antimicrobials in the management of dental infections will be the better than oral antibiotics in terms of clinical , microbial and oral- health quality of life parameters. This will be a three-arm, parallel, comparative, randomized study with the aim of assessing the efficacy of intra-canal medication and oral antibiotics in reducing the infection and treatment of odontogenic infections, based on signs and symptoms and microbial count. The study will be performed in child participants between the age group of 3 to 11 years presenting with acute odontogenic infections. Participants will be randomized by block randomization. The treatment duration of the study will be at least 5 days or maximum 7 days depending upon the response. Participants will be assessed on Day 3 and Day 5/7. Concurrently, the oral health-related quality of life (OHRQoL) following these clinical interventions in children will be recorded and again on Day 14. Quantitative assessment of microorganisms seen in the root canals and the changes seen in the microbial flora through the treatment will help us to determine the best antimicrobial agent to be used in the management of odontogenic infections.