Dementia Clinical Trial
Official title:
Fish Oil and Alpha Lipoic Acid in Mild Alzheimer's Disease
The purpose of this study is to determine the effect of fish oil and the antioxidant alpha lipoic acid on factors in the blood that are associated with the progression of Alzheimer's Disease (AD).
Alzheimer's disease (AD) is a serious condition associated with increased inflammation,
cholesterol, and oxidative stress (a condition involving an excess of free radicals and a
decrease in antioxidant levels). Fish oil and alpha lipoic acid, which have few side
effects, may help relieve these problems; therefore, these supplements may slow the
progression of AD, particularly when given in combination. This study will evaluate the
effect of fish oil and alpha lipoic acid on inflammation, lipid levels, and oxidative
stress.
Participants in this study will be randomly assigned to receive fish oil alone, fish oil and
alpha lipoic acid, or placebo for 1 year. AD rating scales as well as urine and blood tests
will be used to assess participants. Participants will have monthly clinic visits during the
study to monitor adverse events and to undergo various laboratory tests.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05686486 -
Gentle Gymnastics and Relationship Between Family Caregivers and Residents With Dementia in Nursing Homes
|
N/A | |
| Terminated |
NCT05451693 -
Outreach-ER: A Dementia Care Intervention Program
|
||
| Recruiting |
NCT05820919 -
Enhancing Sleep Quality for Nursing Home Residents With Dementia - R33 Phase
|
N/A | |
| Enrolling by invitation |
NCT06040294 -
Dementia and Disability Simulation for College Nursing Students' Senior Activity Facilitation Skills
|
N/A | |
| Completed |
NCT05114187 -
An Internet-Based Education Program for Care Partners of People Living With Dementia
|
N/A | |
| Recruiting |
NCT06322121 -
Vascular Aspects in Dementia: Part 2
|
||
| Active, not recruiting |
NCT03676881 -
Longitudinal Validation of a Computerized Cognitive Battery (Cognigram) in the Diagnosis of Mild Cognitive Impairment and Alzheimer's Disease
|
||
| Completed |
NCT04426838 -
Cognitive Behavioral Therapy for Insomnia for the Dementia Caregiving Dyad
|
N/A | |
| Recruiting |
NCT03462485 -
Pilot Study of the Effects of Playing Golf on People With Dementia
|
N/A | |
| Active, not recruiting |
NCT03677284 -
Managing Time With Dementia: Effects of Time Assistive Products in People With Dementia
|
N/A | |
| Completed |
NCT03849937 -
Changing Talk Online (CHATO) Study
|
N/A | |
| Recruiting |
NCT06284213 -
Biomarkers for Vascular Contributions to Cognitive Impairment and Dementia Consortium
|
||
| Recruiting |
NCT05579236 -
Cortical Disarray Measurement in Mild Cognitive Impairment and Alzheimer's Disease
|
||
| Completed |
NCT05080777 -
Pilot Pragmatic Clinical Trial to Embed Tele-Savvy Into Health Care Systems
|
N/A | |
| Completed |
NCT04571697 -
A Study of Comparing Rates of Dementia and Alzheimer's Disease in Participants Initiating Methotrexate Versus Those Initiating Anti-tumor Necrosis Factor (TNF)-Alpha Therapy
|
||
| Completed |
NCT03583879 -
Using Gait Robotics to Improve Symptoms of Parkinson's Disease
|
N/A | |
| Recruiting |
NCT06033066 -
Financial Incentives and Recruitment to the APT Webstudy
|
N/A | |
| Active, not recruiting |
NCT05204940 -
Longitudinal Observational Biomarker Study
|
||
| Recruiting |
NCT05684783 -
Dementia Champions in Homecare
|
||
| Completed |
NCT03147222 -
Function Focused Care: Fracture Care at Home
|
N/A |