Neuromuscular Electrical Stimulation Via the Peroneal Nerve Reduces Muscle Soreness Following Intermittent Exercise

Delayed Onset Muscle Soreness Clinical Trial

Official title:

Neuromuscular Electrical Stimulation Via the Peroneal Nerve Reduces Muscle Soreness Following Intermittent Exercise

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02018211
• Other study ID #: FK-Sport-001
• Secondary ID: Loughborough
• Status: Completed
• Phase: N/A
• First received: December 17, 2013
• Last updated: June 25, 2015
• Start date: December 2012
• Est. completion date: March 2013

Study information

• Verified date: June 2015
• Source: Firstkind Ltd
• Contact: n/a
• Is FDA regulated: No
• Health authority: United Kingdom: Research Ethics Committee
• Study type: Interventional

Clinical Trial Summary

Numerous techniques are reported to enhance recovery following intense exercise, however there is equivocal support for such claims. A novel technique of neuromuscular electrical stimulation (NMES) via the peroneal nerve has been shown to augment limb blood flow which could enhance recovery following exercise. The present study examined the effects of NMES, compared to graduated compression socks on muscle soreness, strength, and markers of muscle damage and inflammation following intense intermittent exercise.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 21
• Est. completion date: March 2013
• Est. primary completion date: March 2013
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 20 Years to 22 Years

Eligibility

Inclusion Criteria:

• healthy males

• currently playing intermittent sports (such as soccer, field hockey, rugby)

• currently representing their respective sports at either university, county, national or international levels

Exclusion Criteria:

• unhealthy males

• not currently playing intermittent sports (such as soccer, field hockey, rugby)

• not currently representing their respective sports at either university, county, national or international levels

• individuals indicating a history of cardiovascular, metabolic or haematological disorders

• participants reporting a sedentary lifestyle of less than three 30-min physical activity sessions per week

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Delayed Onset Muscle Soreness
• Myalgia

Intervention

Other:
• control
passive recovery following exercise test

Device:
• graduated compression socks
graduated compression socks worn after test exercise
• neuromuscular electrical stimulation device
neuromuscular electrical stimulation device worn after test exercise

Locations

Country	Name	City	State
United Kingdom	School of Sport, Exercise and Health Sciences	Loughborough	Leicestershire

Sponsors (2)

Lead Sponsor	Collaborator
Firstkind Ltd	Loughborough University

Country where clinical trial is conducted

United Kingdom, 

References & Publications (1)

Ferguson RA, Dodd MJ, Paley VR. Neuromuscular electrical stimulation via the peroneal nerve is superior to graduated compression socks in reducing perceived muscle soreness following intense intermittent endurance exercise. Eur J Appl Physiol. 2014 Oct;11 — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	measurement of CK and LDH activity and IL-6, CRP and TBAR concentrations	markers of muscle damage and inflammation following intense intermittent exercise	72 hrs	No
Primary	Perceived muscle soreness (PMS)	perceived muscle soreness (PMS), often referred to as delayed onset muscle soreness (DOMS)	72hrs	No
Secondary	muscle strength		72hrs	No