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Death, Sudden, Cardiac clinical trials

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NCT ID: NCT04540354 Withdrawn - Heart Failure Clinical Trials

Personalised Risk scOre For Implantation of Defibrillators in Patients With Reduced LVEF≤35% and a Low Risk for Sudden Cardiac Death

PROFID-Reduced
Start date: February 1, 2021
Phase: N/A
Study type: Interventional

The objective of the study is to demonstrate that in post-MI patients with symptomatic heart failure who receive optimal medical therapy for this condition, and with reduced LVEF ≤ 35% but low risk for SCD according to a personalised risk score, optimal medical therapy without ICD implantation (index group) is not inferior to optimal medical therapy with ICD implantation (control group) with respect to all-cause mortality.

NCT ID: NCT04540289 Withdrawn - Clinical trials for Myocardial Infarction

Personalised Risk scOre For Implantation of Defibrillators in Patients With Preserved LVEF>35% and a High Risk for Sudden Cardiac Death

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

The objective of the study is to demonstrate that in post-MI patients with preserved LVEF>35% but high risk for SCD according to a personalised risk score, the implantation of an ICD (index group) is superior to optimal medical therapy (control group) with respect to all-cause mortality.

NCT ID: NCT03230773 Withdrawn - Cardiac Arrest Clinical Trials

Use of Public Access Defibrillators by Untrained Bystanders

Start date: April 1, 2020
Phase: N/A
Study type: Interventional

Survival from out-of-hospital cardiac arrest is time critical and diminishes rapidly without appropriate intervention. Bystander CPR at least doubles the chances of survival and the additional use of a public access defibrillator (PAD) can again double overall survival rates. PADs are designed to be easy and simple to use, but whether untrained bystanders can use them safely and effectively is unknown. This study will aim to assess the ability of untrained bystanders to deploy a PAD in a simulated cardiac arrest.

NCT ID: NCT02113722 Withdrawn - Clinical trials for Sudden Cardiac Death

Is Left Stellate Ganglionectomy Beneficial to Patients With Life Threatening Ventricular Arrhythmias

Reduce-SCD
Start date: July 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether the incidence of recurrent life threatening ventricular arrhythmias in patients with an implanted cardiac defibrillator (ICD) can be reduced if a surgical left stellate ganglionectomy is performed.

NCT ID: NCT00593164 Withdrawn - Clinical trials for Death, Sudden, Cardiac

Clinical Study of the LRS ThermoSuit™ System in Post Arrest Patients With Intravenous Infusion of Magnesium Sulfate

Start date: September 2017
Phase: Phase 2
Study type: Interventional

This study will involve the use of therapeutic hypothermia. This prospective cohort pilot study will evaluate the clinical performance of a new device, the ThermoSuit™ System, to achieve therapeutic hypothermia in comatose patients following resuscitation from cardiac arrest, and the impact of the vasodilator, magnesium sulfate, on cooling performance and hemodynamics in these patients. The study hypothesis is that magnesium sulfate will significantly increase the rate of cooling.

NCT ID: NCT00573092 Withdrawn - Clinical trials for Myocardial Infarction

Analyzing Gene Regions That May Interact With the Effectiveness of High Blood Pressure Drugs

Start date: September 2007
Phase: N/A
Study type: Observational

High blood pressure is one of the most common health problems in the United States. There are many drug treatment options for high blood pressure, but these medications are not always effective. People with treated high blood pressure can still suffer from other serious cardiovascular health problems, including heart attack, sudden death, or stroke. Genetic variations may cause some people to be more susceptible to these cardiovascular outcomes despite treatment. This study will identify new gene regions that may influence the effectiveness of high blood pressure drugs in preventing the above mentioned cardiovascular conditions.

NCT ID: NCT00510731 Withdrawn - Clinical trials for Tachycardia, Ventricular

The Ability Of The PD2i Cardiac Analyzer To Predict Risk Of Ventricular Tachyarrhythmic Events

VITAL
Start date: November 2006
Phase: N/A
Study type: Observational

This is a prospective study to evaluating the ability of the PD2i Cardiac Analyzer to predict the risk of serious heart rhythm abnormalities in high-risk patients that do not already have an Implantable Cardioverter Defibrillator.