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A Trial of Enteral Colostrum on Intestinal Permeability in Critically Ill Patients

Critical Illness Clinical Trial

Official title:
Effects of Colostrum Supplement on Intestinal Permeability in Hospitalized Patients With Enteral Feeding in Intensive Care Unit

Clinical Trial Summary

The effects of colostrum on intestinal permeability in critical ill patients has not been investigated. In current trial, intensive care unit patients with enteral feeding will receive either enteral colostrum or maltodextrin as placebo.

Clinical Trial Description

A randomized, double blind, controlled trial will be conducted in general intensive care unit (ICU) in Tehran, Iran. After a full review of the inclusion and exclusion criteria and explanation of the risks and benefits of the study, written consent form will be completed. Intervention patients will be received 20 g/day of colostrum along with enteral formula and control patients will be received maltodextrin along with enteral formula. Patients will be evaluated for plasma endotoxin and plasma zonulin. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03186716
Study type Interventional
Source National Nutrition and Food Technology Institute
Contact
Status Completed
Phase N/A
Start date June 11, 2017
Completion date March 11, 2018
View Details
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