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NCT ID: NCT03792984 Completed - Clinical trials for Polycystic Ovary Syndrome

The Effect of Calcium and Vitamin D Supplements on Metabolic and Hormonal Disturbances in Polycystic Ovary Syndrome Patients

Start date: December 1, 2016
Phase: Phase 3
Study type: Interventional

The aim of this study is to investigate the safety and metabolic-hormonal efficiency of supplementation vitamin D deficient/insufficient PCOS women with (calcium +vitamin D + metformin) for 8 weeks compared to (placebo+ metformin).

NCT ID: NCT03740308 Recruiting - Primary Teeth Clinical Trials

Evaluating the Performance and Efficiency of Zirconia Crowns in Treating Primary Teeth

Start date: May 17, 2018
Phase: N/A
Study type: Interventional

This randomized clinical trial aims to compare the clinical outcomes of two full‑coronal-coverage restorations (locally-made preformed Zirconia crowns [LMP] and NuSmile Zirconia crowns [Nu/ZR]) in treating carious primary teeth. Amongst the children attending the clinics of the Dental School at Damascus University, the ones having an indication for crowns restorations will be screened and if they are conformant to the inclusion criteria then they will be recruited until 60 teeth are reached (30 teeth for LMP/ZR restorations and 30 for Nu/ZR restorations).

NCT ID: NCT03728894 Completed - Behavior, Child Clinical Trials

Oral Sedation With and Without Nitrous Oxide

Start date: November 17, 2018
Phase: Phase 3
Study type: Interventional

Aims: The objective of the current study was to evaluate the effectiveness of oral midazolam-hydroxyzine with/without nitrous oxide. Design: This was a randomized split mouth, cross over and triple-blinded clinical study. Thirty uncooperative healthy children aged six to nine, whose needed dental treatments.

NCT ID: NCT03725995 Completed - Burning Nose Clinical Trials

Using Intranasal Midazolam (INM) and Lidocaine for Uncooperative Children

INM
Start date: June 1, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

Aims: The objective of the current study was to evaluate the effectiveness of topical lidocaine in relieving pain related to INM administration. Design: This was a blinded, randomized placebo-controlled trial. Sixty-three uncooperative children, aged 4 - 11.

NCT ID: NCT03678805 Recruiting - Impaction of Tooth Clinical Trials

The Effect of Surgical Interventions to Assist Orthodontic Movement of Impacted Maxillary Canines

Start date: July 2, 2018
Phase: N/A
Study type: Interventional

Impacted canine causes many problems for patients, such as absorption and damages to the adjacent teeth roots, as well as aesthetic problems. Correction of this problem requires a lengthy time. Therefore, many methods have been suggested to accelerate the movement of impacted canines with the help of surgical procedures.

NCT ID: NCT03667508 Recruiting - Posterior Crossbite Clinical Trials

Effectiveness of Rapid and Slow Maxillary Expansion in Treating Posterior Crossbite

Start date: March 19, 2018
Phase: N/A
Study type: Interventional

This study will evaluate the efficacy of rapid maxillary expansion (RME) and slow maxillary expansion (SME) in treating posterior crossbite using cone beam computed tomography. The study sample will consist of 32 patients who suffer from a skeletal posterior crossbite. The sample will be allocated randomly into two groups: RME group and SME group. The skeletal and dento-alveolar changes occurring after treatment will be assessed by using cone beam computed tomography(CBCT) radiographs.

NCT ID: NCT03659188 Recruiting - Clinical trials for Malocclusion, Angle Class II, Division 1

Comparison Between Two Methods in the Acceleration of the Retraction of Upper Canines

Start date: September 2, 2018
Phase: N/A
Study type: Interventional

Patients at the Orthodontic Department of University of Damascus Dental School will be examined and subjects who meet the inclusion criteria will be included. Then, initial diagnostic records (diagnostic gypsum models, internal and external oral photographs, as well as radiographic images) will be studied to ensure that the selection criteria are accurately matched. The aim of this study is to compare flapless bone cutting by mechanical drills to evaluate the acceleration of the retraction of upper canines versus traditional bone cutting by piezo-surgery in comparison with a control group without bone cutting after extraction of upper first premolars in class II type I patients.

NCT ID: NCT03659097 Recruiting - Clinical trials for Malocclusion, Angle Class I

Acceleration of Alignment of Crowded Lower Anterior Teeth

Start date: September 2, 2018
Phase: N/A
Study type: Interventional

Patients at the Orthodontic Department of University of Damascus Dental School will be examined and subjects who meet the inclusion criteria will be included. Then, initial diagnostic records (diagnostic gypsum models, internal and external oral photographs, as well as radiographic images) will be studied to ensure that the selection criteria are accurately matched. The aim of this study is to compare two groups of patients with moderate crowding of the lower anterior teeth First group (Experimental): the patients in this group will be treated with orthodontic fixed appliances + surgery to the alveolus of the lower anterior teeth in order to induce remodeling of the bony structures and enhance orthodontic movement. Second group (Control): the patients in this group will be treated using fixed appliances with any acceleration method.

NCT ID: NCT03648515 Active, not recruiting - Malocclusion Clinical Trials

Evaluation of the Accuracy of Measurements Made on Images Taken From the Mouth for Dental Arches

Start date: June 15, 2018
Phase:
Study type: Observational

The general trend in the orthodontic practice is to become digital in many aspects. Since 1980s, digital photographs have been available and they play a principal role in the orthodontic practice for documentation and diagnosis purposes. Now photographs have an important role in teaching, scientific research and medical examination. Successful orthodontic treatment is based on a comprehensive diagnosis and treatment planning. A few of the fundamental factors in the diagnosis are the spacing condition, tooth size, arch form and dimensions, as well as the tooth-arch discrepancies. Intraoral photographs' major role is to enable orthodontists to document and analyze the occlusal relationships as well as the dental and soft-tissue features in order to arrive at a good diagnosis and an appropriate treatment plan. In 1975, Robert Little developed Little's irregularity index (LII). The index was proposed to assess teeth irregularity, crowding, relapse, and alignment of anterior teeth as it measured the linear displacements in the horizontal plane between contact points of anterior teeth, ignoring vertical displacement, from mesial surface of one canine to the contra-lateral one. The sum of the 5 liner measurements of displacements was the LII score. The higher the index value, the more severe irregularity of the teeth was. LII has been originally developed for mandibular incisors to study relapse; however, researchers have used it to assess upper and lower incisors irregularity Tooth-size-arch-length discrepancy (TSALD) is widely used on study models to assess the level of harmony between tooth size and the supporting basal bone. Bolton analysis is another important measurement used to identify disharmony between maxillary and mandibular tooth size which is considered an important factor to ensure the success of orthodontic treatment. With the application of the suggested formulas, the overall ratio should be 91.3% (±1.91) and the partial (anterior) ratio should be 77.2% (±1.65). The validity and reliability of performing the above mentioned analyses on images taken of the dental arches have not been evaluated yet in the literature. This is the aim of the current project.

NCT ID: NCT03647241 Recruiting - Clinical trials for Malocclusion of Anterior Teeth

Evaluation of Self-ligating Brackets Plus Minor Surgery in Treating Crowded Cases of Malocclusion

Start date: August 15, 2018
Phase: N/A
Study type: Interventional

Patients at the Orthodontic Department of University of Damascus Dental School will be examined and subjects who meet the inclusion criteria will be admitted then the initial diagnostic records (diagnostic gypsum samples - internal and external oral photographs as well as radiographic images) will be studied to ensure that the selection criteria are accurately matched. The aim of this study is to compare three groups of patients with severe crowding of the upper anterior teeth: - Group 1 : Patients will be treated using self-ligating brackets - Group 2 : Patients will be treated using self-ligating brackets associated with flapless corticotomy. - Group 3 : Patients will be treated using traditional brackets (i.e. brackets positioned on the labial surface of the teeth) At the end of leveling and aligning phase, we will compare the self-ligating brackets and traditional brackets ( the acceleration of teeth movement, dental and alveolar changes and other variables ) Also, there is an intention to study the effectiveness of using flapless corticotomy with the self-ligating brackets.