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NCT ID: NCT03918226 Completed - Clinical trials for Tuberculosis; Abdomen

Acute Presentation and Management of Abdominal Tuberculosis: A Ten-year Experience at a Tertiary Care Center in Pakistan

Start date: May 1, 2008
Phase: N/A
Study type: Interventional

A prospective interventional study was conducted in Services Instituton of Medical Sciences all patients who underwent emergency laparotomy from 2008-2018 due to abdominal tuberculosis. Data were analyzed using SPSS version 21

NCT ID: NCT03902132 Completed - Backache, Low Clinical Trials

Core Muscle Stability on Low Back Pain and Quality of Life in Post- Menopausal Women

Start date: March 1, 2018
Phase: N/A
Study type: Interventional

Low back pain, postural dysfunction, loss of balance control and stability are musculoskeletal changes that occur over life span due to aging process and are inevitable. Core stability exercises are an effective means to counteract these changes.The study was executed with initially n=35 subjects selected as per proposal, but only n=24 subjects completed the study with n=14 in experimental group and n=10 in control group. Experimental group received core stability exercises and control group received conventional physical therapy treatment for 12 weeks. Baseline assessment was done, then at 6 week and again at end of intervention.Following outcome measures were used in study Numeric pain rating scale (NPRS), Utain quality of life (UQOL), Oswestry disability index (ODI), manual muscle testing (MMT) flexion and extension. Data was analysed using Statistical package for social sciences SPSS- 21.

NCT ID: NCT03896685 Not yet recruiting - Tuberculosis Clinical Trials

Evaluating Newly Approved Drugs in Combination Regimens for Multidrug-Resistant TB With Fluoroquinolone Resistance (endTB-Q)

endTB-Q
Start date: June 2019
Phase: Phase 3
Study type: Interventional

endTB-Q Clinical Trial is a Phase III, randomized, controlled, open-label, non-inferiority, multi-country trial evaluating the efficacy and safety of two new, all-oral, shortened regimens for multidrug-resistant tuberculosis (MDR-TB) with fluoroquinolone resistance.

NCT ID: NCT03894449 Enrolling by invitation - Iron-deficiency Clinical Trials

Probing the Synergistic Effect of Pre-Biotics & Iron Fortificants in Anemic Subjects

Start date: July 2019
Phase: Phase 1/Phase 2
Study type: Interventional

Hypothesis: Synergistic effect of pre-biotics and iron fortificants will enhance the bioavailability of iron; thereby improving the body iron reserves. A double blind, randomized controlled trail will be conducted on iron deficient female adults (age 18-25 years) in order to determine the synergistic effect of pre-biotics and iron fortificants in anemic human subjects. 75 iron deficient females will be randomly divided into 5 groups (D0, D1, D2, D3 and D4), each having 15 study subjects and will be given varying doses of FeSO4 and NaFeEDTA and Inulin and GOS. Blood samples will be collected from overnight fasted women from each group on monthly basis up to three months. Various biomarkers for iron absorption, LFTs, RFTs, and Immunoglobulins will be estimated.

NCT ID: NCT03887364 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Icing and Airflow Stimulation in Obstructive Lung Diseases

Start date: February 2, 2018
Phase: N/A
Study type: Interventional

A randomized controlled trial in which icing and airflow stimulation for reduction of dyspnea in patients of obstructive lung disease was done which is characterized as condition of infection described by constant improvement of perpetual constraint of flow of air that is partially reversible and incorporates chronic bronchitis, emphysema and small airway diseases . The tools used were RR, Spirometry, Saturation, Borg Scale, MRC scale, shuttle walk test and St George's Respiratory Questionnaire (St.GRQ) score. Pulse oximeter measured the saturation levels and respiratory rates were alse observed. Borg scale measured rate of perceived exertion ranges from 6(easy physical activity) and 20(worst activity) and MRC measure dyspnea levels. In St.GRQ score between 1 to 8 is symptoms related and 9 to 17 was activity related.Literature review indicate that icing and airflow stimulation reduce dyspnea in patients of obstructive lung diseases.

NCT ID: NCT03885557 Completed - Hamstring Tightness Clinical Trials

Dynamic Oscillatory Stretch Technique Versus Static Stretching In Reduced Hamstring Flexibility

Start date: March 1, 2018
Phase: N/A
Study type: Interventional

This study compared the effects of dynamic oscillatory stretch technique (DOS) and static stretching (SS) technique in order to improve hamstring extensibility in healthy individuals with asymptomatic hamstring tightness. Half of study participants received DOS whereas other half received static stretching technique.

NCT ID: NCT03884920 Not yet recruiting - Diabetes Mellitus Clinical Trials

Effective Enhancement of Glucose Tolerance and Prevention of Diabetes Mellitus Type 2 by Polyherbal Formulation

Phase-1
Start date: March 20, 2019
Phase:
Study type: Observational

Primary protocol to this study is to develop a natural remedy to prevent diabetes mellitus in pre-diabetic state and elaborate the effectiveness of polyherbal formulation for carrying out Phase-II, III and IV. It also aimed at to see the level of difference of glucose tolerance and impaired fasting glucose and impaired glucose tolerance between pre-diabetic and diabetic to evaluate the potential benefit for treatment of insulin resistance and sensitivity. To see the for prevention of Diabetes Mellitus (DM) and stopping / delaying the onset of DM.

NCT ID: NCT03883750 Recruiting - Clinical trials for Niemann-Pick Diseases

Induced Pluripotent Stem Cells for Niemann Pick Disease

IPSNPABC
Start date: June 19, 2018
Phase:
Study type: Observational

Establishment of individualized human cellular disease models based on induced pluripotent stem cells that reflect the broad heterogeneous phenotypic spectrum of Niemann Pick disease

NCT ID: NCT03881813 Completed - Relapse Clinical Trials

Effectiveness of Two Types of Fixed Lingual Retainers in Preventing Mandibular Incisor Relapse

Start date: November 12, 2017
Phase: N/A
Study type: Interventional

The study evaluates effectiveness of two types of fixed retainers in post orthodontic patients. Half of the subjects are randomly allocated Group 1 retainer (FRC) and other half is given Group 2 retainer (MSW) and followed for a period of one year.

NCT ID: NCT03880292 Not yet recruiting - Spinal Deformity Clinical Trials

Spinal Deformity Intraoperative Monitoring.

Start date: May 15, 2019
Phase: N/A
Study type: Interventional

A multicenter, international prospectively collected patient cohort undergoing high-risk spinal cord level surgery or spinal osteotomy procedures will be enrolled to establish the incidence of intraoperative alerts in high-risk spinal cord cases, and explore factors associated with mitigating injury. Baseline, intraoperative, and postoperative characteristics, including demographics, radiological features, lower extremity motor score (LEMS), procedure, anesthetic agents used, and baseline blood pressure will be recorded for either adult patients or pediatric patients.