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NCT ID: NCT03662022 Not yet recruiting - Leprosy Clinical Trials

Post ExpOsure Prophylaxis for LEprosy in the Comoros and Madagascar

PEOPLE
Start date: January 2, 2019
Phase: Phase 3
Study type: Interventional

This is a cluster randomized trial on effectiveness of different modalities of Single Double Dose of Rifampicin Post-Exposure Prophylaxis (SDDR-PEP) for leprosy in the Comoros (Anjouan and Mohéli) and Madagascar. The study aims to identify which approach to the selection of contacts for post exposure prophylaxis is most effective to reduce incident leprosy, and to Interrupt ongoing transmission from asymptomatic persons in the process of developing multibacillary leprosy.