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NCT ID: NCT03404479 Not yet recruiting - Knee Osteoarthritis Clinical Trials

Trial to Evaluate Efficacy and Safety of Combination of Diacerein and Celecoxib Administered in Patients With Knee OA

DIA IIT_01
Start date: January 17, 2018
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the pain relief effect of Co-administration of Diacerein with Celecoxib in patients with knee osteoarthritis compared with single administration of each drug.

NCT ID: NCT03404024 Recruiting - Clinical trials for Acute Myocardial Infarction

Safety and Efficacy Study of Gene Therapy for Acute Myocardial Infarction in Korea

Start date: December 5, 2017
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and clinical efficacy of VM202RY injected via transendocardial route using C-Cathez® catheter (Celyad, S.A., Belgium) in subjects with AMI. - Stage 1: Evaluation of safety and tolerability of VM202 injection - Stage 2: Evaluation of safety and efficacy of VM202 injection

NCT ID: NCT03403972 Completed - Clinical trials for Simvastatin Pharmacokinetics and Gut Microbiome

Evaluate the Effects of the Environmental Change in Intestine by Antibiotics on the Pharmacokinetic Characteristics of Simvastatin in Healthy Male Volunteers

Start date: December 6, 2017
Phase: Phase 1
Study type: Interventional

This phase 1 clinical trial is to evaluate the effects of the environmental change in intestine by antibiotics on the pharmacokinetic characteristics of simvastatin in healthy male volunteers. For change of intestine environment, especially the gut microbiota, investigators will administer PO vancomycin for 7 days, tid.

NCT ID: NCT03403556 Not yet recruiting - Type 2 Diabetes Clinical Trials

High-intensity Rosuvastatin vs. Moderate-intensity Rosuvastatin/Ezetimibe in High Atherosclerotic Cardiovascular Disease Risk Patients With Type 2 Diabetes

Start date: January 2018
Phase: Phase 4
Study type: Interventional

To assess the efficacy and safety of moderate-intensity rosuvastatin/ezetimibe compared to high-intensity rosuvastatin in high atherosclerotic cardiovascular disease risk patients with type 2 diabetes

NCT ID: NCT03403296 Completed - Clinical trials for Stage II-III Gastric Cancer

A Validation Study of Relationships Among Genomic Gene Expression Profile, Prognosis and Prediction of Adjuvant Chemotherapy Benefit With Capecitabine and Oxaliplatin in Gastric Cancer Stage II and III (6th AJCC) Patients After D2 Surgery (CLASSIC)

Start date: July 13, 2016
Phase: N/A
Study type: Observational

The purpose of this study is to validate a pre-defined single-patient classifier algorithm for predicting prognosis and benefit from adjuvant chemotherapy for patients who underwent D2 gastrectomy for stage II and III gastric cancer. This algorithm classifies gastric cancer into five groups according to its molecular characteristics based on RNA expression levels. The prognosis and response from adjuvant chemotherapy will be different according to prognostic and predictive clusters respectively based on these groups, thus this algorithm can identify as patients which will have benefit from adjuvant chemotherapy or which will not. Consequently, this algorithm can be translated into clinical practice to help doctors who decide the necessity of adjuvant chemotherapy after D2 gastrectomy for patients who had diagnosed stage II and III gastric cancer.

NCT ID: NCT03402308 Recruiting - Clinical trials for Muscular Sarcoidosis

Effect of Schisandra Chinensis Extract on Musculoskeletal Biomakers in Relatively Sarcopenic Adults: a RCT

Start date: June 1, 2017
Phase: N/A
Study type: Interventional

The investigators conduct a randomized, double-blind, placebo-controlled study to investigate the effects of the SCE on muscle strength, muscle mass, and muscle function in healthy adults for 12 weeks.

NCT ID: NCT03401827 Recruiting - Clinical trials for Pancreatic Adenocarcinoma

The Effect of Gemcitabine Plus Nab-paclitaxel as Secondary Chemotherapy in Advanced Pancreatic Cancer

Start date: January 20, 2018
Phase: Phase 4
Study type: Interventional

Pancreatic cancer is a very poor prognosis and has a high mortality rate. The clinical results have improved somewhat with the combination therapy of chemotherapy as the first-line treatment. However, effective secondary chemotherapy after these first-line treatment failures is limited. Recently, FOLFIRINOX has been used in patients with locally advanced or metastatic pancreatic cancer who have good performance in Korea. Gemcitabine + nab-paclitaxel (GnP) as a second-line treatment after FOLFIRINOX may be expected to be considerable. The aim of this study was to evaluate the efficacy of GnP as a second-line treatment after failed FOLFIRINOX treatment for locally advanced or metastatic pancreatic ductal adenocarcinoma.

NCT ID: NCT03401801 Recruiting - Neuropathic Pain Clinical Trials

Impact of Local Anesthetic Volume During Ultrasound-guided Stellate Ganglion Block

Start date: November 21, 2017
Phase: N/A
Study type: Interventional

The purpose of this study was to compare the temperature changes of the upper extremities when using local anesthetic of various volume (4ml, 6ml, 8ml) in the ultrasound guided stellate ganglion block.

NCT ID: NCT03401775 Completed - Aging Clinical Trials

Evaluation of the Effects of the New Program for Cognitive Enhancement and Improvement in the Elderly

Start date: December 23, 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effect of cognitive rehabilitation program on the improvement of cognitive functions in normal elderly subjects.

NCT ID: NCT03401593 Not yet recruiting - Clinical trials for Permanent Pacemaker Implantation

Long Term Evaluation and Management of Atrial Fibrillation in Pacemaker Patients

Start date: January 2018
Phase: N/A
Study type: Interventional

This study is prospective randomized study which was performed in multicenter (General Hospital) in Korea. Inclusion criteria is patients who developed atrial fibrillation/flutter/tachycardia after pacemaker implantation among AF-pacemaker study (ClinicalTrials.gov Identifier: NCT03303872). The purpose is to investigate the recurrence rate of AF/AFL/AT in both groups after randomization for 60 months (5 years) in patients post pacemaker implantation and assess long term clinical results.