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NCT ID: NCT03177850 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Effect of Acetazolamide on Sleep Related Breathing Disturbances in Patients With Respiratory Disease at Altitude

Start date: June 2017
Phase: Phase 4
Study type: Interventional

In this trial, the investigators will evaluate the effect of acetazolamide (375 mg per day) vs. placebo on sleep related breathing disturbances at altitude in patients with COPD.

NCT ID: NCT03177837 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Effect of Acetazolamide on Exercise Performance in Patients With Respiratory Disease at Altitude

Start date: June 2017
Phase: Phase 4
Study type: Interventional

In this trial, the investigators will evaluate the effect of acetazolamide (375 mg per day) vs. placebo on exercise performance at altitude in patients with COPD.

NCT ID: NCT03177811 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Effect of Acetazolamide on Postural Control in Patients With Respiratory Disease at Altitude

Start date: June 2017
Phase: Phase 4
Study type: Interventional

In this trial, the investigators will evaluate the effect of acetazolamide (375 mg per day) vs. placebo on postural control at acute altitude exposure in patients with COPD.

NCT ID: NCT03173508 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Effect of Acetazolamide on Right Ventricular Function at Rest in Patients With Respiratory Disease at Altitude

Start date: May 24, 2017
Phase: Phase 4
Study type: Interventional

This trial will evaluate the effect of acetazolamide (375 mg per day) vs. placebo on right ventricular function at acute altitude exposure in patients with COPD.

NCT ID: NCT03172429 Recruiting - Clinical trials for High Altitude Pulmonary Hypertension

Cerebral Tissue Oxygenation in Highlanders/Lowlanders

Start date: May 24, 2017
Phase: N/A
Study type: Observational [Patient Registry]

The purpose of the current study is to evaluate the cerebral tissue oxygenation of Kyrgyz highlanders with high altitude pulmonary hypertension (HAPH) by performing a longitudinal cohort study. To this end, the investigators will invite the same highlanders who participated in the study in 2012 to undergo follow-up examinations in 2017, in order to allow comparisons of current results with baseline data from 2012.

NCT ID: NCT03167034 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Effect of Acetazolamide on Right Ventricular Function During Exercise in Patients With Respiratory Disease at Altitude

Start date: May 24, 2017
Phase: Phase 4
Study type: Interventional

This trial will evaluate the effect of acetazolamide (375 mg per day) vs. placebo on right ventricular function during exercise at acute altitude exposure in patients with COPD.

NCT ID: NCT03165890 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease (COPD)

Effect of Acetazolamide on Cognition in Patients With Respiratory Disease at Altitude

Start date: May 24, 2017
Phase: Phase 4
Study type: Interventional

Randomized, placebo controlled trial evaluating the effect of acetazolamide on cognition in lowlanders with chronic obstructive pulmonary disease travelling from 760 m to 3200 m.

NCT ID: NCT03165656 Recruiting - Clinical trials for High Altitude Pulmonary Hypertension

Right Ventricular Function at Rest in Highlanders/Lowlanders

Start date: May 24, 2017
Phase: N/A
Study type: Observational [Patient Registry]

The purpose of the current study is to evaluate the progression of right ventricular function and dimension in Kyrgyz highlanders with high altitude pulmonary hypertension (HAPH) by performing a cross sectional case-control study.

NCT ID: NCT03165032 Recruiting - Clinical trials for High Altitude Pulmonary Hypertension

Right Ventricular Function During Exercise in Highlanders/Lowlanders

Start date: May 24, 2017
Phase: N/A
Study type: Observational [Patient Registry]

The purpose of the current study is to evaluate the right ventricular function during graded cycling on an ergometer by transthoracic echocardiography in Kyrgyz highlanders with high altitude pulmonary hypertension (HAPH) by performing a cross-sectional case-control study.

NCT ID: NCT03165019 Recruiting - Sleep Apnea Clinical Trials

Time Course and Prognostic Significance of Pulmonary Artery Pressure in Highlanders.

Start date: May 24, 2017
Phase: N/A
Study type: Observational [Patient Registry]

The purpose of the current study is to evaluate the clinical and physiologic course of Kyrgyz highlanders with high altitude pulmonary hypertension (HAPH) by performing a longitudinal cohort study. To this end, the investigators will invite the same highlanders who participated in the study in 2012 to undergo follow-up examinations in 2017, in order to allow comparisons of current results with baseline data from 2012.