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NCT ID: NCT03775642 Recruiting - Clinical trials for Contraception Behavior

Debunking Myths About Contraceptive Safety Among Women in Kingston, Jamaica

Start date: November 21, 2018
Phase: N/A
Study type: Interventional

The primary hypothesis is that the intervention video - based on strategies from cognitive psychology - can correct women's misinformation about long-acting reversible contraception (LARC) and result in higher use of LARC. While there are no direct benefits to participants from being in the study, the research could benefit women in general by providing evidence to help prevent unintended pregnancy. Unlike many interventions that are not feasible for scaling up once shown to be effective in changing people's behavior, the proposed intervention has been carefully designed to impose a low burden to clinic staff and require few resources for translating to wider use. Thus, the investigators expect the intervention to have high potential for influencing clinical care and research for addressing the overall goal of reducing unintended pregnancy.

NCT ID: NCT03763656 Recruiting - Anemia, Sickle Cell Clinical Trials

Pharmacokinetics of Oral Hydroxyurea Solution (SHORT TITLE)

Start date: November 20, 2018
Phase: Phase 2
Study type: Interventional

An open label, safety and pharmacokinetic study of oral hydroxyurea solution administered to children from 6 months to 17.99 years (i.e. to the day before 18th birthday), with a 12 15 month treatment period for each participant. The study treatment duration will be for 6 months at the maximum tolerated dose [MTD], which is usually reached by 6 months after initiation of treatment. For patients in whom time to MTD is longer than 6 months or not achieved at all, the maximum duration of study treatment will be 15 months.

NCT ID: NCT03744091 Active, not recruiting - Healthy Clinical Trials

Evaluation of the Pharmacokinetics of Prana P1 Capsules

Start date: July 16, 2018
Phase: Phase 1
Study type: Interventional

This is a single dose clinical trial to assess the Pharmacokinetics of two (2) dosages; 10 mg and 20mg of THC: THCa of Prana P1 bionutrients in healthy volunteers.

NCT ID: NCT03707288 Not yet recruiting - Back Pain Clinical Trials

Back Pain in Medical Students at The University of the West Indies, Mona, Jamaica

Start date: October 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to identify the prevalence of back pain in preclinical second year and clinical fourth/fifth year medical students at the University of the West Indies; to assess their knowledge, attitude and practice of good spine health; and to determine the outcome of a standardize spine exercise program on one group, the clinical second year medical students, using a prospective randomized control design.

NCT ID: NCT03626441 Completed - Clinical trials for Postoperative Nausea and Vomiting

The Effect of Ginger on the Incidence of Postoperative Nausea and Vomiting

Start date: December 2, 2017
Phase: Phase 2
Study type: Interventional

This study evaluates the effectiveness of ginger on the incidence of postoperative nausea and vomiting in patients undergoing gynaecological surgery. Half the patients were given an oral dose of ginger preoperatively and half received placebo.

NCT ID: NCT03488264 Completed - Quality of Life Clinical Trials

Stigma, Self-management, & Quality of Life in SCD

Start date: February 13, 2018
Study type: Observational

Many individuals with sickle cell disease experience both a poor quality of life and stigma. Individuals with SCD often experience high levels of stigma which can be a barrier to good self-management and hinder quality of life. The purpose of this research is to improve understanding of the relationships between stigma, self-management, and quality of life in SCD in the United States and Jamaica. The findings from this project will contribute to the development of a tool to measure self-management strategies and will also guide the development of interventions to improve SCD self-management.

NCT ID: NCT03478982 Recruiting - Epilepsy Clinical Trials

Inpatient, Dose-Ranging Study of Staccato Alprazolam in Epilepsy With Predictable Seizure Pattern

Start date: March 16, 2018
Phase: Phase 2
Study type: Interventional

This is a multi-center, double-blind, randomized, parallel group, dose-ranging study to investigate the efficacy and clinical usability of STAP-001 in adult (18 years of age and older) subjects with epilepsy with a predictable seizure pattern. These subjects have an established diagnosis of focal or generalized epilepsy with a documented history of predictable seizure episodes. This is an in-patient study. The subjects will be admitted to a Clinical Research Unit (CRU) or Epilepsy Monitoring Unit (EMU) for study participation. The duration of the stay in the in-patient unit will be 2-8 days. One seizure event per subject will be treated with study medication. The duration and timing of the seizure event and occurrence of subsequent seizures will be assessed by the Staff Caregiver(s)1 through clinical observation and confirmed with video electroencephalogram (EEG).

NCT ID: NCT03449940 Completed - Clinical trials for Erectile Dysfunction

Penile Fracture: A Comparison of Erectile Function After Immediate Repair Versus Delayed Repair

Start date: January 2015
Phase: N/A
Study type: Interventional

To prospectively compare erectile function at 12 months, utilizing the abbreviated International Index of Erectile Function-5 (IIEF-5) score, for men treated with an immediate repair versus a delayed repair.

NCT ID: NCT03269110 Active, not recruiting - Asthma Clinical Trials

Folic Acid Clinical Trial: Follow up of Children (FACT 4 Child)

Start date: July 1, 2017
Phase: N/A
Study type: Observational

FACT 4 Child is a follow up study of mothers who participated in the Folic Acid Clinical Trial (NCT01355159) and their children at 4-6 years of age to determine the effect of high dose folic acid supplementation on social impairments associated with Autism Spectrum Disorders (ASDs), and deficiencies in a range of executive function and emotional and behavioural problems in young children, and the risk of death.

NCT ID: NCT03036813 Active, not recruiting - Sickle Cell Disease Clinical Trials

Study to Evaluate the Effect of Voxelotor Administered Orally to Patients With Sickle Cell Disease (GBT_HOPE)

Start date: December 2016
Phase: Phase 3
Study type: Interventional

A Phase 3, Double-blind, Randomized, Placebo-controlled, Multicenter Study of Voxelotor Administered Orally to Patients With Sickle Cell Disease