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NCT ID: NCT03796780 Recruiting - Clinical trials for Cardiovascular Risk Factor

Comparison of Extra-Virgin and Refined Olive Oil on Some Cardiovascular Risk Factors

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

Consumption of extra-virgin olive oil has beneficial effects on cardiovascular risk factors. The purpose of this study is to compare the effects of extra-virgin olive oil and refined olive oil, in adjunct to conventional medical treatment, in improving liver enzymes, plasma lipid profile and inflammatory markers in patients with cardiovascular risk factors.

NCT ID: NCT03796520 Recruiting - Epilepsy Clinical Trials

Validation Study of the Simplified Seizure Classification Algorithm

VASSCA
Start date: April 2, 2018
Phase:
Study type: Observational

An algorithm has been developed for simplified classification of epileptic seizures, in order to optimize choice of antiepileptic drugs. The objective of this study was to clinically validate the algorithm.

NCT ID: NCT03795974 Active, not recruiting - Clinical trials for Cerebral Palsy, Spastic

Efficacy of Allogeneic Umbilical Cord Derived Hematopoietic and Mesenchymal Stem Cells in Cerebral Palsy

Start date: July 23, 2017
Phase: Phase 2
Study type: Interventional

Cerebral palsy(CP) consisted of a group of developmental disability in the field of motor function and is one of the major problems of pediatric neurology and at the present time there is no standard curative medical or surgical treatment for it .Stem cell therapy is one of a new and hopeful therapeutic methods of therapy for CP .This double blind study designed for the evaluation of safety and therapeutic effects of intrathecal hematopoietic and mesenchymal stem cells derived from allogenic umbilical cord in change and probable improvement of developmental functions of spastic CP participants between 4-14 years old and comparing with control group of CP participants without cell therapy . 108 cases recruited and randomly divided to 3 groups of 36 cases : hematopoietic stem cells derived from allogenic umbilical cord , Mesenchymal cells derived from allogenic umbilical cord and control group without injection and appearance simulating lumbar puncture without awareness of the patients and evaluators . Developmental functions and spasticity evaluated before intervention and will be done 1 , 3 , 6 and 12 months after injection . During this period neuro rehabilitation will be continued . Brain neuroimaging were done at the recruitment time and will be repeated after 12 months .

NCT ID: NCT03786211 Recruiting - Anesthesia Clinical Trials

IANB Success Rate With and Without Panoramic Help

Start date: November 12, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

Since it is difficult to achieve anesthesia in lower jaw and the success rate of IANB is low and there are a lot of anatomic variations for the location of inferior alveolar nerve in different races, investigators decided to compare the success rate of inferior alveolar nerve block, with and without using a panoramic radiograph in Bandar Abbas population, and see if using a panoramic radiograph can increase the preciseness of the injection.

NCT ID: NCT03773029 Not yet recruiting - Clinical trials for Peritoneal Dialysis Patients

The Effects of Isoflavones on Cardiovascular and Bone Metabolism Markers in Peritoneal Dialysis Patients

Start date: December 2018
Phase: N/A
Study type: Interventional

The aim of this double-blind randomized clinical trial is to determine the effects of isoflavones on cardiovascular disease risk factors, bone metabolism markers, serum concentrations of fructoseamine and advanced glycated end products in peritoneal dialysis patients. Forty-four patients from shafa clinic and Dr.najafi's clinic will randomly assign to either isoflavone or placebo group. The patients in isoflavone group will receive 100 mg soy isoflavone (as 2 capsules) daily for 8 weeks, while the placebo group will receive identical placebo. At the baseline and the end of the study,7 ml blood will be collected from each patient after a 12-14-hours fasting and serum concentrations of Lp (a), MDA, hs-CRP, sICAM-1, bone alkaline phosphatase, osteocalcin, N-telopeptide, osteoprotegerin, RANKL, iPTH, triglyceride, total cholesterol, HDL-C, LDL-C, fructoseamine, carboxymethyl lysine, pentosidine, glucose, albumin, calcium and phosphorous will be measured. Furthermore, blood pressure measurements will be performed twice with a ten-minute interval between testing

NCT ID: NCT03766074 Active, not recruiting - Depression Clinical Trials

Vitamin D Supplementation in Patients With Depression

Start date: May 6, 2018
Phase: N/A
Study type: Interventional

Groups (intervention group receives 50000 IU vitamin D and control group receives placebo) through a random allocation. After 8 weeks, blood sample will be collected from each participant. The studied indices (inflammatory (IL-1β, IL-6, hs-CRP), PTH, platelet serotonin, serum oxytocin, serum 25(OH) D, depression status and anthropometry indices) will be evaluated at beginning and end of interventional period.

NCT ID: NCT03755700 Recruiting - Clinical trials for Coronary Artery Disease

Vitamin E and N-acetylcysteine for Preventing Contrast-Induced Acute Kidney Injury After Coronary Artery Catheterization

Start date: November 1, 2018
Phase: Phase 3
Study type: Interventional

In a double-blinded randomized clinical trial, all patients undergoing coronary artery catheterization who will met our criteria, will be enrolled into three groups to receive either, vitamin e, n-acetylcysteine, or placebo. The aim of study will be to compare the superiority of vitamin e over n-acetylcysteine for the prevention of contrast-induced acute kidney injury (CIAKI).

NCT ID: NCT03753113 Recruiting - Clinical trials for Androgenetic Alopecia

Efficacy and Safety Study to Compare Topical Herbal Solution and Minoxidil 5% in Male Pattern Hair Loss

Start date: November 1, 2018
Phase: Phase 3
Study type: Interventional

The purpose of this study is evaluating the efficacy and safety of a topical herbal solution in males for the treatment of Androgenetic alopecia.

NCT ID: NCT03747081 Recruiting - Clinical trials for Cerebral Venous Thrombosis

Efficacy Comparison of Warfarin Versus Rivaroxaban CVT

Start date: September 1, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

With regard to Cerebral Venous Thrombosis (CVT) importance as a life threatening disease, specific care is necessary, Known anti-coagulants have limitations.Vitamin K antagonists such as Warfarin, require laboratory monitoring and exact administration starting and maintenance dose. although Rivaroxaban(selective and direct Xa factor antagonist ) has no monitoring and no drug interaction. This study aim to focus on efficacy of Warfarin versus Rivaroxaban.

NCT ID: NCT03737422 Recruiting - Metabolic Syndrome Clinical Trials

The Effects of Hesperidin and Flaxseed in Metabolic Syndrome

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

To study the effects of Hesperidin and flaxseed supplement in patients with metabolic syndrome, 50 patients will be randomly allocated to control group or 2 capsules Hesperidin and 30 gram flaxseed for 12 weeks; both groups will be advised to adherence the investigators' diet and exercise program too. At the first and the end of the intervention, lipid profiles, blood pressure, blood sugar, anthropometric factors will be assessed and compared between groups.