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NCT ID: NCT02372006 Recruiting - Rhabdomyosarcoma Clinical Trials

Trial of Afatinib in Pediatric Tumours

Start date: April 29, 2015
Phase: Phase 1/Phase 2
Study type: Interventional

Open-label, dose escalation, monotherapy, basket trial with biomarker specific MTD expansion cohort/Phase II part. The trial will consist of 2 parts: 1. Dose finding part to determine the MTD 2. Biomarker specific MTD expansion cohort/Phase II part to assess clinical anti-tumour activity in included tumour types