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NCT ID: NCT06365710 Recruiting - Clinical trials for Orthopedic Procedures, Physical Therapy Modalities, Postoperative Care, Rehabilitation, Wrist Fractures

Physiotherapy vs Telerehabilitation After Volar Plating of Distal Radius Fracture

Start date: November 24, 2022
Phase: N/A
Study type: Interventional

Trial purpose is to research the outcome comparing traditional physiotherapy vs telerehabilitation after volar plating of distal radius fracture. Patients with distal radius fracture that meet the operative criteria set by the Finnish Current Care guidelines are randomized (1:1 computer generated sequence with random block size) to two parallel groups and will undergo operative treatment and traditional physiotherapy vs telerehabilitation. Baseline data is collected preoperatively and patients are followed at 1, 3 and 12 months after enrollment. The primary end-point is 3 months and the primary outcome is the Patient-Rated Wrist Evaluation (PRWE).

NCT ID: NCT06365112 Recruiting - Acetabulum Fracture Clinical Trials

Endoscopic Acetabulum Surgery

Start date: April 2024
Phase: Early Phase 1
Study type: Interventional

Try to develop an endoscopic surgical technique to treat acetabulum fractures

NCT ID: NCT06323603 Recruiting - Clinical trials for Occupational Exposure

Biomonitoring of Occupationally Populations Exposed to Micro and Nanoplastic

Start date: June 30, 2023
Phase:
Study type: Observational

The biomonitoring study aims to evaluate genotoxic damage and other parameters of exposure in different occupational exposed populations that work directly with different plastics.

NCT ID: NCT06322511 Recruiting - Family Relations Clinical Trials

Dialogical Family Guidance PostDoc Study

DFG II
Start date: January 2, 2024
Phase: N/A
Study type: Interventional

This new family intervention, called Dialogical Family Guidance (DFG) is developed to target family needs especially in families with a child with neurodevelopmental disorders. PhD study showed, that this intervention is functioning with this target group. Participants (families) experienced that they got information, guidance to ordinary life and that the DFG-therapists were listening to them and above all, helping with individual problems and questions. DFG include six meetings and professionals need to attend on a 3-day long education before using this intervention.

NCT ID: NCT06321133 Recruiting - Acute Bronchiolitis Clinical Trials

High Flow Nasal Cannula Weaning in Acute Bronchiolitis

Start date: February 13, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical study is to compared two different strategies to end high flow nasal cannula treatment in acute bronchiolitis. This study compared the immediate ending of high flow treatment to weaning strategy, in which the flow rate is gradually decreased. The aim is to assess if the immediate ending shortens the hospitalization time and whether it is a safe strategy.

NCT ID: NCT06310759 Recruiting - Clinical trials for Urothelial Carcinoma

Prospective Validation Study of High Volume Urine DNA Testing in Individuals With Suspicion of Urothelial Cancer

UROSCOUT-1
Start date: January 8, 2024
Phase:
Study type: Observational

Urothelial cancers of the bladder and upper urinary tract account for over 200,000 deaths and 600,000 diagnoses annually worldwide. The most common presenting symptom is hematuria (blood in urine), triggering a cascade of tests, including an invasive examination of the bladder using a flexible scope (cystoscopy). Millions of cystoscopies are performed every year worldwide for patients presenting with hematuria, but only 10% result in a cancer diagnosis. The UROSCOUT-1 trial is a prospective multicenter observational study that explores the potential of urine tumor DNA (utDNA) testing to replace a significant portion of cystoscopies in the diagnostic setting for hematuria or other reasons to rule out urothelial cancer. The goal is to enhance patient quality of life, reduce healthcare costs, and address increased workloads in urology centers. Sample collection will be conducted by mail, and the samples will be analyzed in a blinded manner, without knowledge of which patients are diagnosed with cancer. Random subsampling will be applied to cancer-negative patients to achieve an approximate 1:1 ratio between cancer-positive and -negative patients.

NCT ID: NCT06286917 Recruiting - ALS Clinical Trials

Initiation of Noninvasive Ventilation in ALS Patients With Chronic Respiratory Insufficiency

InNIVALS
Start date: March 5, 2024
Phase: N/A
Study type: Interventional

This research will study whether noninvasive ventilation (NIV) used to treat chronic respiratory insufficiency in patients with amyotrophic lateral sclerosis (ALS) can be initiated as successfully in the outpatient setting as in the conventional inpatient setting, and what the costs of these alternative initiation methods are.

NCT ID: NCT06285461 Recruiting - Obesity Clinical Trials

Food Intake, Endocrine Factors and Brown Fat

FoodBAT
Start date: February 20, 2024
Phase: N/A
Study type: Interventional

This study will investigate how the acute intake of foods with high and low hedonic reward differentially affects brown adipose tissue and the interplay between gut peptides, brown fat, and the brain (gut-BAT-brain axis).

NCT ID: NCT06283966 Recruiting - Clinical trials for COPD (Chronic Obstructive Pulmonary Disease)

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

THARROS
Start date: February 21, 2024
Phase: Phase 3
Study type: Interventional

This study will evaluate the effect of triple ICS/LAMA/LABA therapy with BGF MDI 320/14.4/9.6 μg on cardiopulmonary outcomes relative to LAMA/LABA therapy with GFF MDI 14.4/9.6 μg in a population with COPD and elevated cardiopulmonary risk.

NCT ID: NCT06262958 Recruiting - Clinical trials for Substance Use Disorders

Recognition and Early Intervention for Alcohol and Substance Abuse in Adolescence in Adolescent

REAL-SMART
Start date: August 7, 2017
Phase: N/A
Study type: Interventional

ASSIST mini-intervention is applied in an electric form in adolescent outpatients to see if it