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NCT ID: NCT06323902 Completed - Macular Holes Clinical Trials

Autologous Platelet-rich Plasma as a Treatment for Macular Holes

Start date: October 25, 2022
Phase:
Study type: Observational

For a series of patients with full-thickness macular hole, an autologous plasma rich in growth factors was developed in the form of a clot and applied to the retinal defect. These patients were followed up for a period of one year, obtaining substantial improvement both anatomically and functionally.

NCT ID: NCT06278584 Completed - Clinical trials for Meibomian Gland Dysfunction

iLux Treatment for Meibomian Gland Dysfunction

MGD
Start date: October 15, 2020
Phase: N/A
Study type: Interventional

Summary: Purpose: To compare the safety and efficacy of eyelid treatment with the ILux®-MGD Treatment System in one session versus five sessions of mechanical meibomian gland expression (MMGE) in patients with moderate to severe meibomian gland dysfunction (MGD). Methods: Prospective, randomized, open-label, controlled clinical trial comparing one session of the ILux® MGD Treatment System versus five sessions of MMGE in both eyes of 130 patients aged ≥18 years with OSDI scores ≥13, total MGS of 15 in the lower lid of each eye and NI-TBUT <10 s, who were randomized 1:1 to ILux® or MMGE.

NCT ID: NCT06268691 Completed - Dengue Clinical Trials

Sustainable Reduction of Dengue in Colombia: Vector Breeding Site Intervention With an Insecticidal Coating

Start date: February 4, 2019
Phase: N/A
Study type: Interventional

Effective control of Aedes aegypti mosquitoes in breeding sites with high reproductive rates could have a major impact on reducing arbovirosis in endemic communities. The application of a safe, effective, low cost and sustained insecticide coating (IC) could be an affordable response to dengue for local health services. Therefore, a cluster randomised trial for the application of a new vector control tool (insecticidal coating of water containers) was conducted in the metropolitan area of Cúcuta, Colombia. The IC is an aqueous solution containing polymeric microcapsules of insecticides and insect growth regulators (pyriproxyfen-PPF (0.063%) and alphacypermertrin-ACM (0.07%) in suspension, without interaction between them, development by INESFLY®, Spain. The main questions it aims to answer are: Whether the control of the main breeding sites of Aedes mosquitoes, through the application of insecticide coating, in clusters of dwellings, could reduce dengue transmission in a sustainable way, compared to untreated clusters, in Cúcuta, Colombia. Whether the control of the main breeding sites of Aedes mosquitoes through the application of insecticide coating, in clusters of dwellings, could reduce the Aedes Indices in a sustainable way, compared to untreated clusters. The initial preparation phases: i) socialization ii) A safety evaluation to determine the health risks of IC in domestic water containers; iii) The determination of the effects and efficacy of IC on Aedes aegypti. The Baseline study to characterise the study clusters from entomological, epidemiological and socio-economic approaches was carried out in 2019-2020. The IC application phase in the intervention arm was carried out between Nov-2021 and Jan-2022, with the respective monitoring of the safety of IC use. This was followed by entomological monitoring. Finally, the 9-month post-intervention evaluation. Epidemiological data were obtained from the National Public Health Surveillance System - SIVIGILA. The study was conducted in 20 clusters of 2000 dwellings each, where 10 clusters were randomly assigned to the control arm and 10 clusters to the intervention arm. In order to determine the effect of IC application in household tanks, the dengue incidence and entomological indices are compared in the study clusters. The data are analysed under the difference in difference approach. Additionally, the acceptance of IC in the intervened communities and local health services is determined.

NCT ID: NCT06248437 Completed - Sarcopenia Clinical Trials

Prototype of Innovative Food Product to Improve Respiratory and Peripheral Muscle Function in Humans

HIC1
Start date: March 30, 2019
Phase:
Study type: Observational

HIC1® compound has a presence in the form of a gel, which facilitates its oral intake (direct or diluted with water) and also administration through gastrostomy tubes or nasogastric tubes. All received a dose of 30 grams of gel.

NCT ID: NCT06238739 Completed - Postoperative Pain Clinical Trials

Optimal Temperature Control in Body Contouring Procedures

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare different strategies for normothermia prevention in patients undergoing body contouring and other Aesthetic Plastic Surgery procedures. The main question(s) it aims to answer are: - Do active measures have an impact on preventing hypothermia in patients undergoing cosmetic procedures? - Does an active normothermia prevention protocol have any impact in the clinical setting? Four different protocols will be used for patient peroperative preparation for normothermia.

NCT ID: NCT06200324 Completed - Clinical trials for Very Low Birth Weight Infant

Clinical Outcomes of Ready-to-Use Parenteral Nutrition in Low Birth Weight Newborns in Colombia 2017-2023

NUMETA
Start date: March 1, 2017
Phase:
Study type: Observational

The proposed study aims to assess the clinical outcomes of using ready-to-use parenteral nutrition, specifically Numeta G13E, compared to individualized parenteral nutrition in neonates with very low birth weight. Conducted in a level 4 neonatal intensive care unit from March 2017 to March 2023, the study focuses on growth parameters (weight, head circumference, height), growth velocity, and the incidence of complications. The retrospective open-cohort observational design involves a sample of 284 infants, 142 in each group, considering a 95% confidence level and 80% power. The study addresses the need for a local evaluation of the efficacy of ready-to-use parenteral nutrition in this vulnerable population.

NCT ID: NCT06159036 Completed - Female Clinical Trials

Effects of a Strength Training Program in Inertial Machines on Bosco Test in Youth Volleyball Players

Start date: September 26, 2022
Phase: N/A
Study type: Interventional

Objective: To determine the effect of strength training in inertial machines, on SJ CMJ and CMJ with arms; in youth volleyball players from the city of Cartago. Methodology: A quasi-experimental study of quantitative order was carried out and takes up an empirical-analytical approach, quasi-experimental with pre-test - post-test evaluation. 32 female volleyball players, belonging to the minor category of the Fénix G Club of the city of Cartago Valle Results: Both groups showed significant improvements in jump height, flight time, strength and power in the protocol that was carried out during the 12 weeks of intervention, but there was no statistically significant difference between the control groups (P = 0.356). , experimental (P = 0.984) Conclusions: Keywords: Inertial machines, Squat jump, Countermovent Jump, Abalakov

NCT ID: NCT06124183 Completed - Clinical trials for Mental Health Wellness 1

Emotional Intelligence Program for Adolescents With Antisocial Behavior (DYNAMIS)

DYNAMIS
Start date: January 11, 2022
Phase: N/A
Study type: Interventional

This study assessed the effectiveness of an emotional intelligence program based on the Salovey and Mayer model among adolescents exhibiting antisocial behavior. A quasi-experimental design was employed, involving 231 Colombian adolescent offenders (122 in the experimental group). A 12-session psychological protocol was implemented. The primary question it aims to address is whether it is feasible for adolescents with antisocial behavior to reduce negative emotional symptoms related to mental health, such as anxiety, stress, and depression, while simultaneously improving their emotional skills. It was observed that those who completed the program showed significant improvements in emotional intelligence, emotional balance, and resilience while experiencing a decrease in emotional symptoms, particularly in stress.

NCT ID: NCT06092294 Completed - Clinical trials for Decision Making in Soccer Players and Executive Functions

Numerical Superiority and Inferiority Compared With Conventional Training on PTK and Executive Functions in Soccer

Start date: July 3, 2023
Phase: N/A
Study type: Interventional

There is a great need to establish reliable evaluation and intervention protocols to improve the tactical component, decision making (DM) and procedural tactical knowledge (PTK) in soccer. Objectives: to determine the effects of a 12-week follow up numerical superiority and numerical inferiority tactical training program on PTK, which will be evaluated by calculating offensive, defensive and global effectiveness indexes (EI) of 24 amateur male soccer players, as well as the effect on their executive functions. Method: randomized controlled trial, with two groups in parallel, experimental group (EG) and control group (CG), with different measurements over time (pretest, intermediate test 1, intermediate test 2 and posttest).

NCT ID: NCT05992129 Completed - Healthy Clinical Trials

Influence of Foot Types on Collegiate Athletes

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

The purpose of the study is to assess whether high or low arch foot types influence the overall performance of the athlete.