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NCT ID: NCT03258723 Not yet recruiting - Diabetes Clinical Trials

Diabetes Prevention With Lifestyle Intervention and Metformin Escalation

LIME
Start date: January 2018
Phase: Phase 4
Study type: Interventional

Specific Aim: Implement an evidence-based diabetes prevention pragmatic trial for high risk pre-diabetic individuals of Caribbean-descent to reduce the incidence of diabetes. Hypothesis: This study seeks to test the hypothesis that implementation of a lifestyle intervention, with escalation to Metformin therapy will lower the incidence of diabetes among the highest risk pre-diabetic individuals of Caribbean-descent.

NCT ID: NCT02321150 Active, not recruiting - Pterygium Clinical Trials

A Novel Technique for the Removal of Pterygiums

Start date: December 2013
Phase: N/A
Study type: Interventional

The aim of this study is to introduce a new surgical technique for the removal of pterygiums that entails the use of bipolar electrocautery to secure the graft, rather than sutures. With this, the objective is to evaluate the benefits of a new technique for pterygium surgery with respect to postoperative patient comfort, surgery time, cost and recurrence rate.

NCT ID: NCT02313805 Recruiting - Diabetes Mellitus Clinical Trials

The Effect of a Checklist on the Quality of Education During Insulin Initiation by Trained Medical Students

Start date: July 2014
Phase: N/A
Study type: Interventional

Diabetes prevalence continues to rise worldwide, leading to the increasing use of insulin. This especially applies to developing countries where the needle-and-syringe method of administration remains the most affordable and effective form of hyperglycemic treatment. Competent health care professionals are required to ensure safe insulin initiation. The investigators will evaluate a teaching intervention on insulin initiation for medical students, and whether after experiencing that intervention the use of a checklist, during simulate insulin initiation, improves the education they provide to patients.

NCT ID: NCT02266303 Recruiting - Insulin Checklist Clinical Trials

The Effect of a Checklist on the Education of Simulated Patients During Insulin Initiation

Start date: July 2014
Phase: N/A
Study type: Interventional

The increasing prevalence of diabetes is associated with increased insulin use. In developing countries it is frequently necessary to use insulin, with the needle and syringe method of administration being the cheapest approach. Competence of health care professionals is required to safely initiate insulin. The investigators will evaluate whether using a checklist during insulin initiation with a needle and syringe, can improve the safety and efficacy of its use.

NCT ID: NCT02059122 Active, not recruiting - Infectious Diseases Clinical Trials

Sensitivity Study of Diagnostic for Early Detection of Dengue Infection

Start date: April 2011
Phase: N/A
Study type: Observational

This study is a multi-site trial assessing the sensitivity of DENV Detect™ NS1 ELISA versus standard reference tests (e.g. PCR or viral culture) for dengue diagnosis in the US and internationally. The DENV Detect™ NS1 ELISA serves as an aid in the clinical laboratory diagnosis of early stages of Dengue infection in patients with clinical symptoms consistent with Dengue infection. This test is intended to be used on sera obtained within the first 7 days of symptoms. DENV Detect™ NS1 ELISA results (positive or negative) must be confirmed by testing with a reference standard test. Subjects will be patients who present with symptoms consistent with dengue infection, such as fever and myalgia. After informed consent is obtained and the subject is screened for eligibility, 2 diagnostic samples will be collected. The first will be collected within the first 7 days of symptoms onset, and the second will be collected at least 7 days later, between the 10th and 21st days post-onset of symptoms. ELISA and reference tests will be performed by different operators who are laboratory staff members. These staff members, blinded to each other's results, will evaluate the samples from each method independently.

NCT ID: NCT01994811 Recruiting - Diabetes Clinical Trials

Eastern Caribbean Health Outcomes Research Network (ECHORN)

ECHORN
Start date: April 2013
Phase: N/A
Study type: Observational

The Eastern Caribbean Health Outcomes Research Network (ECHORN) is a collaborative research study that examines the lifestyles, eating habits, and health behaviors associated with cancer, diabetes and heart disease in adult men and women living in the Eastern Caribbean.

NCT ID: NCT01002521 Not yet recruiting - Diabetes Mellitus Clinical Trials

Wound Healing In Diabetes (WHy) Study

WHy
Start date: December 2009
Phase: N/A
Study type: Observational

This observational study aims to identify risk factors and molecular mechanisms of impaired wound healing, to guide better foot care in the diabetic population.

NCT ID: NCT00002446 Completed - HIV Infections Clinical Trials

Safety and Effectiveness of Fluconazole Versus SCH 56592 to Treat Thrush in HIV-Positive Patients

Start date: August 1998
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the safety and effectiveness of 2 treatments for thrush (a fungal infection of the mouth and throat) in HIV-positive patients. Fluconazole is a drug that is commonly used to treat thrush. SCH 56592 is a new drug that will be compared to fluconazole.