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Cardiac Metabolic Modulator Treatment for Improvement of Diastolic Function in Patients With Coronary Heart Disease

Coronary Heart Disease Clinical Trial

Official title:
Cardiac Metabolic Modulator Treatment for Improvement of Left Ventricular Diastolic Function in Patients With Coronary Heart Disease: a Prospective, Randomized Controlled Study

Clinical Trial Summary

Based on accumulating evidence showing that impaired cardiac energetic metabolism plays important role in the mechanism of cardiac diastolic dysfunction,the study is designed to evaluate whether metabolic modulator treatment with trimetazidine could have beneficial effects on patients with coronary heart disease(CHD) and ventricular diastolic dysfunction.This study is a prospective,randomised,open-label trial to assess the efficacy of trimetazidine treatment in improving diastolic function in CHD patients with diastolic dysfunction.

Clinical Trial Description

The primary objective of this trial is to determine whether the 24-week trimetazidine therapy, as an adjunct to routine treatment for CHD, would improve diastolic function in patients with ischemic heart disease compared to the routine treatment. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03887013
Study type Interventional
Source China National Center for Cardiovascular Diseases
Contact Yan Zhao
Phone 008615810783328
Email zhaoyanfuwai@163.com
Status Not yet recruiting
Phase Phase 4
Start date March 25, 2019
Completion date December 2020
View Details
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