Coronary Disease Clinical Trial
— WeChatOfficial title:
Web basEd soCial Media tecHnology to Improvement in Adherence to Dual anTiplatelet Therapy Following Drug-Eluting Stent Implantation (WeChat), a Randomized Controlled Branch on Antiplatelet of RESCIND Study
Few studies have attempt to improve DAPT adherence through social media. The investigators will explore the prevalence of DAPT discontinuation and prove the hypothesis that using social media will improve DAPT adherence among patients requiring DAPT following DES implantation.
Status | Recruiting |
Enrollment | 760 |
Est. completion date | September 30, 2021 |
Est. primary completion date | March 30, 2021 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - aged =18 years - diagnosed CHD and underwent DES implantation - provide written informed consent Exclusion Criteria: - pregnancy - malignant tumor or end-stage disease with a life expectancy of <1 year; - refusal to use social media - refusal to provide written informed consent for this study |
Country | Name | City | State |
---|---|---|---|
China | Guangdong General Hospital | Guangzhou | Guangdong |
Lead Sponsor | Collaborator |
---|---|
Guangdong Provincial People's Hospital | Dongguan People's Hospital, First People's Hospital, Shunde China, Guangzhou Panyu Central Hospital, Maoming General Hospital |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Rate of Discontinuation of Dual Antiplatelet Drug | Defined as discontinuation of any dual antiplatelet drug owing to patients' own discretion, including bleeding or non-compliance rather than doctors' advice. Changing of DAPT medication between ticagrelor and clopidogrel under doctors' advice will not be identified as dual antiplatelet drug discontinuation; changing of such under own discretion will be identified as such | 1 year | |
Secondary | Medication Adherence | Dual antiplatelet therapy (DAPT) adherence according to proportion of days covered (PDC) by prescription. | 1 year | |
Secondary | Number of Participants with Major Adverse Cardiovascular Events | All-cause mortality,target vessel revascularization, non-fatal myocardial infarction, and stroke | 1 year |
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