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Coronary Artery Disease Progression clinical trials

View clinical trials related to Coronary Artery Disease Progression.

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NCT ID: NCT03943459 Not yet recruiting - Clinical trials for Coronary Artery Disease Progression

Sirtuin-1 and Advanced Glycation End-products in Postmenopausal Women With Coronary Disease

Start date: June 1, 2019
Phase: Phase 3
Study type: Interventional

Higher consumption of fruits and vegetables promote greater availability of phenolic compounds and these compounds were associated with vascular health. Quercetin, a phenolic compound, is the most abundant natural antioxidant belonging to the group of flavonoids. Quercetin improved lipoprotein metabolism, had antioxidant capacity, produced vasodilating substances in the vascular endothelium and reduced platelet aggregability. Likewise, statins are medications known to reduce cardiovascular events in women with coronary disease by reducing serum LDL-cholesterol. Therefore, a number of metabolic pathways are responsible for vascular health. The serum concentration and gene expression of sirtuin 1 (Sirt1) and RAGE soluble (sRAGE) are directly associated with vascular protection. This study will analyse the influence of atorvastatin and quercetin on serum concentrations and gene expression of Sirt1 and sRAGE in postmenopausal women with stable coronary artery disease.

NCT ID: NCT03788369 Not yet recruiting - Coronary Stenosis Clinical Trials

Evaluation of Effectiveness and Safety of Hybrid Coronary Revascularization

HCR registry
Start date: January 15, 2019
Phase:
Study type: Observational

This study evaluated the effectiveness and safety of Hybrid Coronary Revascularization in real-world practice.

NCT ID: NCT03540381 Completed - Clinical trials for Coronary Artery Disease Progression

Relation Among HDL Functionality, Neoatherosclerosis and Target Lesion Revascularization

Start date: May 1, 2011
Phase:
Study type: Observational

The aim of this study is to evaluate the relation among cholesterol uptake capacity which measure HDL functionality, neoathrosclerosis and target-lesion revascularization.

NCT ID: NCT03533959 Recruiting - Clinical trials for Coronary Artery Disease Progression

To Evaluate the Efficacy of Alirocumab for Neoatherosclerosis by Using OCT, in Comparison With Standard Statin Therapy

POLARIS
Start date: December 18, 2017
Phase:
Study type: Observational

The aim of this study is to evaluate the efficacy of alirocumab for in-stent neoatherosclerosis by using optical coherence tomography, in comparison with standard statin therapy.

NCT ID: NCT03349385 Recruiting - Clinical trials for Coronary Arteriosclerosis

Registry of Secondary Revascularization

REVASEC
Start date: November 22, 2017
Phase:
Study type: Observational [Patient Registry]

The study will evaluate patients with, at least, one previous procedure of coronary revascularization (surgical, percutaneous or both), that are referred for a new, clinically indicated, diagnostic coronary angiography, to describe their clinical characteristics, management, and prognosis, and will propose a prognosis-oriented classification.

NCT ID: NCT03195621 Recruiting - Clinical trials for Coronary Artery Disease

Critical Treatment of Coronary Artery Disease

CTCAD
Start date: July 1, 2016
Phase: N/A
Study type: Interventional

Identifying the critical lesion of coronary artery disease and determining the interventional plan are significant for reducing adverse cardiovascular adverse events. The assessment of critical lesion requires the consideration of plaque morphology, tissue composition, and endometrial stress which leading to rupture. In summary, accurate assessment of critical lesions has high application value. In this study, patients with critical coronary artery disease were divided into two groups: an accurate assessment group and a simple assessment group, with the aim to compare the diagnosis and treatment efficiency as well as prognosis, potential cardiovascular risk, possible "excessive" intervention.

NCT ID: NCT03192579 Completed - Clinical trials for Coronary Artery Disease Progression

Effect of Rosuvastatin and Eicosapentaenoic Acid on Neoatherosclerosis: The LINK-IT Trial

Start date: July 26, 2013
Phase: Phase 4
Study type: Interventional

This study aim to evaluate whether intensive lipid lowering therapy may improve the clinical outcomes in coronary artery disease patients with in-stent neoatherosclerosis, in comparison with standard therapy.