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Clinical Trial Summary

Negative pressure ventilation (NPV) is a non-invasive ventilation mode which provide better lung expansion. The major complication of NPV is decrease blood pressure and affects the hemodynamics. The effects of NPV on chronic obstructive pulmonary disease (COPD) patients with pulmonary rehabilitation program remains unknown.


Clinical Trial Description

Both of NPV or positive pressure ventilation (PPV) has impact of hemodynamics. NPV with cuirass ventilator increases venous return and leads to ventricular filling and increases cardiac output (CO); In contrast to NPV, the effect of PPV in most situations is a decreased venous return and leads to decreased CO. NPV improving ventilation and work of breathing in patients with chronic obstructive pulmonary disease (COPD). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04212559
Study type Observational
Source Fu Jen Catholic University
Contact
Status Completed
Phase
Start date January 1, 2018
Completion date December 31, 2019

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