Congenital Hemiparesis Clinical Trial
Official title:
Comparing the Location of the Motor Cortex in Children Using Two Methods: EEG and TMS
Hypothesis: In typically developing children (TDC), use of conventional EEG landmarks to determine the brain area that controls hand function will not differ from TMS-guided determination of individual motor hotspots. In children with hemiparesis, however, those two locations will diverge. The prediction is that TMS will best guide Transcranial Direct Current Stimulation (tDCS) interventions
Congenital hemiparesis, mainly due to stroke, affects approximately 25% of children with
cerebral palsy. Noninvasive brain stimulation has emerged to influence improvements in hand
function specifically in children with congenital hemiparesis due to stroke.
The use of one type of noninvasive brain stimulation, Transcranial Direct Current Stimulation
(tDCS), in conjunction with rehabilitation training intervention for a child with hemiparesis
proposes a synergistic approach to improving hand function. Application of electrodes over
certain targeted areas are placed with the intent to stimulate and influence neuronal
activity.
Our preliminary evidence suggests that in children with hemiparesis due to stroke, the area
for placement is variable as noted by electroencephalogram (EEG) and Transcranial Magnetic
Stimulation (TMS) measurement methods, influencing the site location of optimal stimulation
for tDCS.
Due to this variation, the optimal site of stimulation warrants investigation for the optimal
placement of tDCS.
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| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02091687 -
Longitudinal Outcomes in Pediatric rTMS and CIT
|