Clinical Trials Logo

Clinical Trial Summary

Healthcare-associated infections (HCAIs) and evolving bacterial resistance are major public health concerns that impact all areas of healthcare. Further work is needed to better understand these healthcare issues so that effective preventive measures can be developed.

The investigators have developed and validated an experimental model for studying the risk factors for bacterial cross contamination in the surgical operating room. The investigators have confirmed in our previous work that intraoperative bacterial transmission events occur frequently both within and between surgical cases and that these transmission events are linked to 30-day postoperative HCAIs and increased patient mortality.

In response, the investigators have implemented various strategies designed to bacterial transmission in the operating room, including anesthesia provider hand hygiene compliance. The investigators' recent work in the intensive care unit suggests that the hand hygiene system the investigators have previously studied could be further optimized.

The investigators now propose to evaluate the effectiveness of a multimodal hand hygiene system enhanced with novel wireless technology designed to facilitate real-time group and individual performance feedback.

The investigators hypothesize that the use of this system will increase hourly hand decontamination events of anesthesia and circulating nurse providers and reduce 30-day postoperative healthcare-associated infections HCAIs (primary outcome), reduce hospital stay duration, and hospital re-admission rates, and mortality(secondary outcomes).


Clinical Trial Description

Healthcare-associated infections (HCAIs) and evolving bacterial resistance are major public health concerns that impact all healthcare arenas. Further work is indicated to better understand these healthcare issues in order that effective preventive measures can be developed.

The investigators have developed and validated an experimental model for studying the mechanisms, risk factors for, and implications of bacterial cross contamination in the surgical operating room. The investigators have confirmed through use of this model that intraoperative bacterial transmission events occur frequently within and between operative cases and that these transmission events are linked to 30-day postoperative HCAIs and to increased patient mortality. In response, the investigators have implemented and evaluated various strategies designed to target risk factors for intraoperative bacterial transmission events including anesthesia provider hand hygiene compliance, improved handling and design of intravascular catheters, and improved environmental decontamination of high-risk objects. While these focused strategies have been successful in reducing transmission events and the incidence of 30-day postoperative infections, the investigators' recent work in the intensive care unit suggests that the hand hygiene system the investigators studied could be further optimized. The investigators now propose to evaluate the effectiveness of a multimodal hand hygiene system enhanced with novel wireless technology designed to facilitate real-time group and individual performance feedback, two evidence-based educational interventions, in reducing 30-day postoperative HCAIs (primary outcome) and intraoperative bacterial transmission events, hospital stay duration, and hospital re-admission rates (secondary outcomes). ;


Study Design


Related Conditions & MeSH terms

  • Complication of Surgical Procedure
  • Infection

NCT number NCT02252562
Study type Interventional
Source Dartmouth-Hitchcock Medical Center
Contact
Status Completed
Phase N/A
Start date September 2013
Completion date August 2015

See also
  Status Clinical Trial Phase
Recruiting NCT02789579 - The Preventive Infection Role of One Week Antibiotics Before Minimally Invasive Upper Tract Lithotomy Early Phase 1
Withdrawn NCT02374294 - TCOT Effectiveness in Preventing Wound Infections in Perineal Resections Phase 2
Completed NCT01757704 - Factors Responsible for the Effectiveness of the Lund De-airing Technique N/A
Recruiting NCT05005117 - Laparoscopic Approach for Emergency Colon Resection N/A
Enrolling by invitation NCT03234543 - Remote Ischemic Conditioning in Abdominal Surgery N/A
Completed NCT04849702 - Comparison of the Clavien-Dindo and Comprehensive Complication Index
Completed NCT04120324 - Incidence of 30 Day Return to Hospital Following Same Day Discharge Total Hip Arthroplasty
Recruiting NCT05761821 - Key Factors of Leadless Pacemaker Implantation With Implantation Site, Complications and Prognosis
Active, not recruiting NCT05795127 - Risk for Reoperation After First MTP Joint Arthrodesis
Completed NCT04550156 - Evaluation of the Introduction of a Colorectal Bundle in Left Sided Colorectal Resections N/A
Recruiting NCT05194943 - Trends and Safety in Revisional Bariatric Surgery in Italy
Not yet recruiting NCT03313986 - Outcomes of Surgical Correction of Penile Curvature in Adult N/A
Enrolling by invitation NCT04456530 - Use of Testosterone to Prevent Post-Surgical Muscle Loss - Pilot Study Phase 2/Phase 3
Completed NCT03125798 - Comparison of LigaSure to Conventional Electrocoagulation in Video-assisted Thoracoscopic Surgery Lobectomy N/A
Completed NCT04226482 - Review of Efficacy of Used ultraSonic Energy Device N/A
Completed NCT01739374 - Efficacy and Safety of Reduced Pelvic Floor Mesh Implants Phase 2/Phase 3
Completed NCT01346709 - Prospective Evaluation of a RIsk Score for Postoperative Pulmonary COmPlications in Europe
Recruiting NCT02212054 - A Trial on Treatments of Hirschsprung Allied Disease N/A
Completed NCT04352699 - Outcomes of Urological Surgery During Periods of Social COVID-19 Containemnt: is it Reasonable to Limit Access to Surgical Care for All?
Completed NCT04683666 - Cardiovascular Risk Factors of Medical and Septic Complications After Laparoscopic Bariatric Surgery