Colorectal Carcinoma Clinical Trial
Official title:
Does Hemodynamic Optimization During and After Colorectal Surgery Result in Improved Intestinal Perfusion, Sustained Intestinal Barrier and Improved Postoperative Recovery?
58 patients undergoing surgery of the large bowel are divided into two groups. The control
group will receive standard care. The intervention group will receive standard care plus
optimization of the blood circulation based on in- or decrease of the output of the heart.
Between group differences are measured primarily by markers of intestinal damage in plasma
and urine. Also CO2 pressure in the stomach lumen is measured (reflecting blood supply to
the gut).
The investigators hypothesize that the intervention group will have less intestinal damage,
improved blood supply to the bowel and improved recovery of the operation compared to the
control group.
n/a
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
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