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Study of ctDNA Guided Change in Tx for Refractory Minimal Residual Disease in Colon Adenocarcinomas

Colorectal Cancer Clinical Trial

Official title:
Proof of Concept Study of ctDNA Guided Change in Treatment for Refractory Minimal Residual Disease in Colon Adenocarcinomas

Clinical Trial Summary

This is a phase 1b, prospective, single arm, non-randomized, open-label clinical trial determining the efficacy of adjuvant trifluridine and tipiracil (TAS-102) in combination with irinotecan in patients with ctDNA positive colon adenocarcinoma.

Clinical Trial Description

Treatment on study will be administered in 14 day cycles. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04920032
Study type Interventional
Source University of California, Irvine
Contact Chao Family Comprehensive Cancer Center University of California
Phone 1-877-827-7883
Email ucstudy@uci.edu
Status Recruiting
Phase Phase 1
Start date August 26, 2021
Completion date December 31, 2025
View Details
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